N5254

Neuraminidase-Agarose aus Clostridium perfringens (C. welchii)

Type VI-A, ammonium sulfate suspension

• Synonym(e): Acylneuraminyl-Hydrolase, Receptor-destroying enzyme, Sialidase
• UNSPSC Code: 12352204
• NACRES: NA.54
• EG-Nummer: 3.2.1.18 (BRENDA, IUBMB)
• MDL number: MFCD00131711
• Specific activity: 20-60 units/g agarose

Eigenschaften

• type: Type VI-A
• Quality Segment: 200
• form: ammonium sulfate suspension
• specific activity: 20-60 units/g agarose
• extent of labeling: 0.6-1.8 units per mL gel, 20-60 units per g agarose
• matrix: beaded agarose
• storage temp.: 2-8°C

Beschreibung

General description

Neuraminidase enzymes are glycoside hydrolase enzymes that catalyze hydrolysis of terminal sialic acid residues. The most well-known are the viral nearamidases, which promote influenza virus release.

Application

Agarose-linked neuraminidase from Clostridium perfringens can be used for the detection of total and desialylated sex hormone-binding globulin in human serum samples.

Neuraminidase from Clostridium perfringens has been used in a study to assess a genetic polymorphism of human serum glycoprotein (inter-α-trypsin-inhibitor). It has also been used in a study to investigate the inhibition of neuraminidase by chemically sulphated glycopeptides.

Physical form

Suspension in 2.0 M (NH₄)₂SO₄-Lösung, pH 7.0

Preparation Note

Hergestellt aus Neuraminidase, Typ VI

Other Notes

1 U setzt 1.0 μmol N-Acetylneuraminsäure pro Minute bei pH 5.0 und 37 °C frei unter Verwendung von NAN-Lactose oder Rinder-Submaxillary Muzin, sofern nicht anders angegeben. Die Preise basieren auf Einheiten mit NAN-Lactose als Substrat.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• Was ist los?: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable