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Merck

N4779

Sigma-Aldrich

5-Nitro-2-(3-phenylpropylamino)benzoic acid

≥98%

Synonym(e):

NPPB

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€ 389,00

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25 MG
€ 119,00
100 MG
€ 389,00

About This Item

Empirische Formel (Hill-System):
C16H16N2O4
CAS-Nummer:
Molekulargewicht:
300.31
MDL-Nummer:
UNSPSC-Code:
12352200
PubChem Substanz-ID:
NACRES:
NA.77

€ 119,00


Voraussichtliches Versanddatum22. Mai 2025


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Assay

≥98%

Form

solid

Löslichkeit

ethanol: 3 mg/mL
DMSO: 37 mg/mL
H2O: insoluble

Lagertemp.

−20°C

SMILES String

OC(=O)c1cc(ccc1NCCCc2ccccc2)[N+]([O-])=O

InChI

1S/C16H16N2O4/c19-16(20)14-11-13(18(21)22)8-9-15(14)17-10-4-7-12-5-2-1-3-6-12/h1-3,5-6,8-9,11,17H,4,7,10H2,(H,19,20)

InChIKey

WBSMIPAMAXNXFS-UHFFFAOYSA-N

Biochem./physiol. Wirkung

Potent chloride channel blocker.

Leistungsmerkmale und Vorteile

This compound is featured on the Chloride Channels page of the Handbook of Receptor Classification and Signal Transduction. To browse other handbook pages, click here.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Agnieszka Dyrda et al.
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The mechanical, rheological and shape properties of red blood cells are determined by their cortical cytoskeleton, evolutionarily optimized to provide the dynamic deformability required for flow through capillaries much narrower than the cell's diameter. The shear stress induced by such
Alwin Scharstuhl et al.
PloS one, 4(8), e6688-e6688 (2009-08-21)
We previously identified curcumin as a potent inducer of fibroblast apoptosis, which could be used to treat hypertrophic scar formation. Here we investigated the underlying mechanism of this process. Curcumin-induced apoptosis could not be blocked by caspase-inhibitors and we could
Valia Verrière et al.
PloS one, 7(5), e37746-e37746 (2012-06-05)
Cystic Fibrosis (CF) is a genetic disease characterised by a deficit in epithelial Cl(-) secretion which in the lung leads to airway dehydration and a reduced Airway Surface Liquid (ASL) height. The endogenous lipoxin LXA(4) is a member of the
Anaïs Merckx et al.
PLoS pathogens, 4(2), e19-e19 (2008-02-06)
Malaria symptoms occur during Plasmodium falciparum development into red blood cells. During this process, the parasites make substantial modifications to the host cell in order to facilitate nutrient uptake and aid in parasite metabolism. One significant alteration that is required
Sheyanth Mohanakumar et al.
American journal of physiology. Heart and circulatory physiology, 315(2), H389-H401 (2018-04-11)
Human lymphatic vessels are myogenically active and respond to sympathetic stimulation. The role of various cations in this behavior has recently been investigated, but whether the anion Cl- is essential is unclear. With ethical approval and informed consent, human thoracic

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