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M8628
α-Methyl-DL-histidin -dihydrochlorid
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Empirische Formel (Hill-System):
C7H11N3O2 · 2HCl
CAS-Nummer:
Molekulargewicht:
242.10
UNSPSC Code:
12352200
PubChem Substance ID:
MDL number:
assay
≥98%
form
powder
color
white
application(s)
cell analysis
SMILES string
Cl.CC(N)(Cc1cnc[nH]1)C(O)=O
InChI
1S/C7H11N3O2.ClH/c1-7(8,6(11)12)2-5-3-9-4-10-5;/h3-4H,2,8H2,1H3,(H,9,10)(H,11,12);1H
InChI key
AABZGRFLFXCQEY-UHFFFAOYSA-N
Lagerklasse
13 - Non Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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Heather Francis et al.
Gut, 61(5), 753-764 (2011-08-30)
In several tumours the endogenous activity of histidine decarboxylase (HDC), the enzyme stimulating histamine synthesis, sustains the autocrine trophic effect of histamine on cancer progression. Cholangiocarcinoma is a biliary cancer with limited treatment options. Histamine interacts with four G-protein coupled
Olga Y Gasheva et al.
American journal of physiology. Gastrointestinal and liver physiology, 316(1), G217-G227 (2018-11-27)
This study aimed to establish mechanistic links between the prolonged intake of desloratadine, a common H1 receptor blocker (i.e., antihistamine), and development of obesity and metabolic syndrome. Male Sprague-Dawley rats were treated for 16 wk with desloratadine. We analyzed the