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Merck

M5170

IgM, Lambda from murine myeloma

clone MOPC 104E, purified immunoglobulin, buffered aqueous solution

Synonym(e):

Mouse IgM-λ

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Über diesen Artikel

UNSPSC Code:
12352203
NACRES:
NA.46
MDL number:
Conjugate:
unconjugated
Clone:
MOPC 104E, monoclonal
Application:
Citations:
11

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Unterstützung erhalten

biological source

mouse

Quality Level

conjugate

unconjugated

antibody form

purified immunoglobulin

clone

MOPC 104E, monoclonal

form

buffered aqueous solution

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

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Dieser Artikel
I3784M6034SAB4200857
antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

purified from hybridoma cell culture

conjugate

unconjugated

conjugate

unconjugated

conjugate

unconjugated

conjugate

-

biological source

mouse

biological source

mouse

biological source

mouse

biological source

-

clone

MOPC 104E, monoclonal

clone

DX, monoclonal

clone

HOPC-1, monoclonal

clone

TEPC 183-SY

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

shipped in

dry ice

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

storage temp.

−20°C

General description

IgM antibodies are present as pentamers in the serum and are produced in response to antigens[1]
IgM, λ from murine myeloma is produced by MOPC 104E tumor line introduced subcutaneously in BALB/c mice. It specifically recognizes mouse IgM, λ. Identity and purity of the immunoglobulin is established by immunoelectrophoresis.

Application

IgM, λ from murine myeloma was used as standard in ELISA[2] and as isotype control in immunohistochemistry applications.

Biochem/physiol Actions

Antigen Specificity: α(1→3) glucose
IgM antibodies are produced initially during B-cell development. IgM participates in opsonization and compliment fixation. Defect in IgM production is observed in X-linked agammaglobulinemia.

Physical form

Solution in 0.05 M Tris, 0.5 M sodium chloride, pH 8.0, containing 0.02% sodium azide

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Lagerklasse

10 - Combustible liquids

wgk

nwg

flash_point_f

Not applicable

flash_point_c

Not applicable


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Jason R Nesbitt et al.
Frontiers in microbiology, 8, 2706-2706 (2018-02-07)
Aspergillus fumigatus is a filamentous fungus that can cause a life-threatening invasive pulmonary aspergillosis (IPA) in immunocompromised individuals. We previously characterized an exo-sialidase from A. fumigatus that prefers the sialic acid substrate, 2-keto-3-deoxy-D-glycero-D-galacto-nononic acid (Kdn); hence it is a Kdnase.
D R Wilson et al.
Protein engineering, 10(5), 531-540 (1997-05-01)
The immunodominant region of the Plasmodium falciparum circumsporozoite protein is comprised mainly of a series of tetrapeptide repeats that can, depending on the starting cadence chosen, be described as (NANP)n, (ANPN)n, (NPNA)n or (PNAN)n in one-letter amino acid code. Data
Establishment of fetal bovine intestinal epithelial cell cultures susceptible to bovine rotavirus infection
Kaushik RS et al
J. Virol. Methods, 148, 182-196 (2008)
Radhey S Kaushik et al.
Journal of virological methods, 148(1-2), 182-196 (2008-01-12)
Mucosal epithelial cells are infected by a wide variety of pathogens and determining their response to infection is critical for understanding disease pathogenesis. A protocol was developed for culturing primary epithelial cells from fetal bovine intestine and the cultured cells
Chithra C Sreenivasan et al.
Virology, 528, 152-163 (2019-01-08)
Influenza viruses are a group of respiratory pathogens that have evolved into four different types: A, B, C, and D. A common feature is that all four types are capable of replicating and transmitting among pigs. Here, we describe the

Global Trade Item Number

SKUGTIN
M5170-1MG04061834059592

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