M1195

Metolazon

≥98% (HPLC), solid

• Synonym(e): 7-Chlor-1,2,3,4-tetrahydro-2-methyl-3-(2-methylphenyl)-4-oxo-6-chinazolinsulfonamid
• Empirische Formel (Hill-System): C₁₆H₁₆ClN₃O₃S
• CAS-Nummer: 17560-51-9
• Molekulargewicht: 365.83
• NACRES: NA.77
• PubChem Substance ID: 24724532
• UNSPSC Code: 12352200
• EC Number: 241-539-3
• MDL number: MFCD00069304
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• assay: ≥98% (HPLC)
• form: solid
• color: white
• solubility: DMSO: >5 mg/mL
• SMILES string: CC1Nc2cc(Cl)c(cc2C(=O)N1c3ccccc3C)S(N)(=O)=O
• InChI: 1S/C16H16ClN3O3S/c1-9-5-3-4-6-14(9)20-10(2)19-13-8-12(17)15(24(18,22)23)7-11(13)16(20)21/h3-8,10,19H,1-2H3,(H2,18,22,23)
• InChI key: AQCHWTWZEMGIFD-UHFFFAOYSA-N
• Gene Information: human ... SLC12A1(6557), SLC12A3(6559)

Beschreibung

Biochem/physiol Actions

Inhibitor of thiazide-sensitive Na⁺-Cl^- cotransporter; antihypertensive; moderate "loop" diuretic.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)