L7418

LAAM -hydrochlorid

≥98% (HPLC), solid

• Synonym(e): α-l-acetylmethadol hydrochloride, (1S)-2-[(2S)-2-(dimethylamino)propyl]-1-ethyl-2,2-diphenylethyl acetate hydrochloride, MK-790 hydrochloride, ORLAAM hydrochloride, levomethadyl acetate hydrochloride
• Empirische Formel (Hill-System): C₂₃H₃₂ClNO₂
• CAS-Nummer: 43033-72-3
• Molekulargewicht: 389.96
• MDL-Nummer: MFCD01723736
• UNSPSC-Code: 12352202
• PubChem Substanz-ID: 329817651

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Arzneimittelkontrolle: USDEA Schedule II; kontrollierte Droge in Deutschland; regulated under CDSA - not available from Sigma-Aldrich Canada
• Farbe: white
• Löslichkeit: H₂O: >5 mg/mL
• Lagertemp.: 2-8°C
• SMILES String: Cl.CC[C@H](OC(C)=O)C(C[C@H](C)N(C)C)(c1ccccc1)c2ccccc2
• InChI: 1S/C23H31NO2.ClH/c1-6-22(26-19(3)25)23(17-18(2)24(4)5,20-13-9-7-10-14-20)21-15-11-8-12-16-21;/h7-16,18,22H,6,17H2,1-5H3;1H/t18-,22-;/m0./s1
• InChIKey: UXBPQRGCVJOTNT-COBSGTNCSA-N
• Angaben zum Gen: human ... OPRM1(4988)

Beschreibung

Biochem./physiol. Wirkung

LAAM hydrochloride is μ opioid receptor agonist.

LAAM hydrochloride is μ opioid receptor agonist. LAAM hydrochloride is a DEA-controlled substance, which has a slow onset, but a long duration of action. LAAM is a useful tool for studying opiate tolerance and cross-reactivity with other μ opioid receptor agonists.

Sonstige Hinweise

DEA Schedule II

Sicherheitshinweise

• Piktogramme: GHS06
• Signalwort: Danger
• H-Sätze: H300,H315,H319,H335,H413
• P-Sätze: P261 - P264 - P301 + P310 - P305 + P351 + P338
• Gefahreneinstufungen: Acute Tox. 2 Oral - Aquatic Chronic 4 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• Lagerklassenschlüssel: 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges