L2885

Lymphotoxin-β Receptor/Fc Chimera human

>95% (SDS-PAGE), recombinant, expressed in NSO cells, lyophilized powder, suitable for cell culture

• Synonym(e): TNF R-related protein, TNF RIII
• MDL-Nummer: MFCD03100005
• UNSPSC-Code: 51111800

Eigenschaften

• Biologische Quelle: human
• Rekombinant: expressed in NSO cells
• Assay: >95% (SDS-PAGE)
• Form: lyophilized powder
• Mol-Gew.: monomer calculated mol wt 49.6 kDa; 70 kDa by SDS-PAGE (reducing) (due to glycosylation)
• Verpackung: pkg of 100 μg
• Lagerbedingungen: avoid repeated freeze/thaw cycles
• Methode(n): cell culture | mammalian: suitable
• Verunreinigungen: endotoxin, tested
• UniProt-Hinterlegungsnummer: P36941
• Lagertemp.: −20°C
• Angaben zum Gen: human ... LTBR(4055)

Beschreibung

Biochem./physiol. Wirkung

LTBR (lymphotoxin β receptor) is a receptor for LIGHT (tumor necrosis factor ligand superfamily member 14) and LT (lymphotoxin)-a1β2. It is present in the epithelial, stromal and myeloid cells. LTBR participates in lymphoid organ development and immune homeostasis. It is also involved in the lipopolysaccharide (LPS)-mediated expression of IL (interleukin)-8.

Physikalische Form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline.

Hinweis zur Analyse

The biological activity is measured by the ability of the immobilized LTβR/Fc to bind LTα2/β1 and LTα1/β2 in a functional ELISA.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 3
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable