L1026

Lidocain

Na+ channel blocker, solid

• Synonym(e): 2-Diethylamino-N-(2,6-dimethyl-phenyl)-acetamid, Lignocain, Xylocain
• Empirische Formel (Hill-System): C₁₄H₂₂N₂O
• CAS-Nummer: 137-58-6
• Molekulargewicht: 234.34
• NACRES: NA.77
• PubChem Substance ID: 24896272
• UNSPSC Code: 12352200
• EC Number: 205-302-8
• MDL number: MFCD00026733
• Form: solid

Eigenschaften

• Produktname: Lidocain, analytical standard
• grade: analytical standard
• Quality Segment: 200
• form: solid
• packaging: vial of 200 mg
• technique(s): HPLC: suitable, chromatography: suitable, gas chromatography (GC): suitable
• impurities: ≤0.5% Total Organic Impurities (Lidocaine related compound H ≤0.10%; ; ; 2,6-Dimethylaniline ≤0.01%; ; ; Any unspecified impurity ≤0.10%; ; ; Total impurities ≤0.5%)
• application(s): forensics and toxicology; pharmaceutical (small molecule)
• SMILES string: CCN(CC)CC(=O)Nc1c(C)cccc1C
• InChI: 1S/C14H22N2O/c1-5-16(6-2)10-13(17)15-14-11(3)8-7-9-12(14)4/h7-9H,5-6,10H2,1-4H3,(H,15,17)
• InChI key: NNJVILVZKWQKPM-UHFFFAOYSA-N
• Gene Information: human ... CYP1A2(1544), SCN10A(6336), SCN11A(11280), SCN1A(6323), SCN2A(6326), SCN3A(6328), SCN4A(6329), SCN5A(6331), SCN7A(6332), SCN8A(6334), SCN9A(6335) ; rat ... Scnn1a(25122)

Beschreibung

General description

Lidocaine is an amide anesthetic, which is used to treat ventricular arrhythmias. It lowers cardiac automaticity and myocardial conduction. Lidocaine inhibits the generation and conduction of nerve impulses. It has an anticonvulsant effect.

Application

Lidocaine has been used to examine its effects in inhibiting lymph flow and protection against envenomation. It has also been used to assess its efficacy as an anti-tussive agent.

Biochem/physiol Actions

Na⁺ Kanalblocker; Klasse IB Antiarrhythmikum.

Packaging

Geliefert In Braunglas-Vials

Sicherheitshinweise

• Piktogramme: GHS07
• Signalwort: Warning
• Gefahrencodes: H302
• Sicherheitshinweise: P264 - P270 - P301 + P312 - P501
• Hazard Classifications: Acute Tox. 4 Oral
• Lagerklasse: 11 - Combustible Solids
• Was ist los?: WGK 3
• PSA (Persönliche Schutzausrüstung): dust mask type N95 (US), Eyeshields, Faceshields, Gloves