J3205

JNJ-1661010

≥98% (HPLC)

• Empirische Formel (Hill-System): C₁₉H₁₉N₅OS
• Molekulargewicht: 365.45
• MDL-Nummer: MFCD00209157
• UNSPSC-Code: 12352200
• PubChem Substanz-ID: 329815405
• NACRES: NA.77

Eigenschaften

• Assay: ≥98% (HPLC)
• Form: solid
• Löslichkeit: DMSO: ≥28 mg/mL
• Ersteller: Johnson & Johnson
• Lagertemp.: 2-8°C
• SMILES String: O=C(Nc1ccccc1)N2CCN(CC2)c3nc(ns3)-c4ccccc4
• InChI: 1S/C19H19N5OS/c25-18(20-16-9-5-2-6-10-16)23-11-13-24(14-12-23)19-21-17(22-26-19)15-7-3-1-4-8-15/h1-10H,11-14H2,(H,20,25)
• InChIKey: BHBOSTKQCZEAJM-UHFFFAOYSA-N

Beschreibung

Biochem./physiol. Wirkung

JNJ-1661010 is a potent and selective fatty acid amide hydrolase (FAAH) inhibitor with >100-fold preferentially selective for FAAH-1 over FAAH-2. FAAH in an integral membrane enzyme within the amidase-signature family. It catalyzes the hydrolysis of several endogenous biologically active lipids and involves in a variety of physiological and pathological processes, including synaptic regulation, regulation of sleep and feeding, locomotor activity, pain and inflammation.

Leistungsmerkmale und Vorteile

This compound was developed by Johnson & Johnson. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklassenschlüssel: 11 - Combustible Solids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable