I9659

Monoclonal Anti-Insulin-like Growth Factor-II antibody produced in mouse

clone 75014, purified immunoglobulin, lyophilized powder

• Synonym(e): Anti-IGF2, Anti-INSIGF
• UNSPSC Code: 51111800
• NACRES: NA.41
• MDL number: MFCD00162567
• Conjugate: unconjugated
• Clone: 75014, monoclonal
• Application: WB
• Citations: 4

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: 75014, monoclonal
• form: lyophilized powder
• species reactivity: human
• technique(s): western blot: 1-2 μg/mL
• isotype: IgG2a
• UniProt accession no.: P01344
• storage temp.: −20°C
• Gene Information: human ... IGF2(3481)

Beschreibung

Immunogen

purified, E. coli-derived recombinant human insulin-like growth factor-II.

Biochem/physiol Actions

Insulin-like growth factors -I and -II are important regulators of signaling that mediates growth and metabolism in cells. Insulin-like growth factor -II (IGF-II) is widely expressed during embryonic stages and regulates the placental development. IGF-II acts via specific receptor, IGF-IIR, the binding does not result in signal transduction, but is a mechanism to restrict the bioavailability of IGF-II. The effects of IGF-II signaling are important in growth of blood vessels (angiogenesis) gene transcription, proliferation and transformation.

Physical form

Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline with 5% trehalose.

Sicherheitshinweise

• Lagerklasse: 13 - Non Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)