I6658

Isradipin

≥98% (HPLC), calcium channel blocker, solid

• Synonym(e): 4-(4-Benzofurazanyl)-1,-4-dihydro-2,6-dimethyl-3,5-pyridindicarbonsäure-methyl-(1-methylethyl)-ester
• Empirische Formel (Hill-System): C₁₉H₂₁N₃O₅
• CAS-Nummer: 75695-93-1
• Molekulargewicht: 371.39
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724517
• NACRES: NA.77
• MDL number: MFCD00153820
• Assay: ≥98% (HPLC)
• Form: solid

Eigenschaften

• Produktname: Isradipin, ≥98% (HPLC), solid
• description: Store under nitrogen
• assay: ≥98% (HPLC)
• form: solid
• color: yellow
• solubility: DMSO: >10 mg/mL
• originator: Novartis
• storage temp.: 2-8°C
• SMILES string: COC(=O)C1=C(C)NC(C)=C(C1c2cccc3nonc23)C(=O)OC(C)C
• InChI: 1S/C19H21N3O5/c1-9(2)26-19(24)15-11(4)20-10(3)14(18(23)25-5)16(15)12-7-6-8-13-17(12)22-27-21-13/h6-9,16,20H,1-5H3
• InChI key: HMJIYCCIJYRONP-UHFFFAOYSA-N
• Gene Information: human ... CACNA1C(775), CACNA1D(776), CACNA1F(778), CACNA1S(779), CACNA2D1(781)

Beschreibung

Application

Isradipine has been used to explore neuroprotective activity.

Biochem/physiol Actions

L-type calcium channel blocker (also referred to as dihydropyridine-type calcium channel blocker); antihypertensive.

L-type calcium channel blocker; antihypertensive.

Isradipine is considered as an active calcium channel blocker, used to treat hypertension.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)