F9786
Fibroblast Growth Factor-Basic Heparin Stabilized human
FGF-Basic, recombinant, expressed in E. coli, sterile-filtered, aqueous solution, suitable for cell culture
Synonym(e):
rhbFGF
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About This Item
Empfohlene Produkte
Biologische Quelle
human
Rekombinant
expressed in E. coli
Sterilität
sterile-filtered
Form
aqueous solution
Wirksamkeit
0.03-3.0 ng/mL ED50/EC50
Qualität
endotoxin tested
Verpackung
pkg of 1 and 5 mL
Methode(n)
cell culture | mammalian: suitable
UniProt-Hinterlegungsnummer
Lagertemp.
2-8°C
Angaben zum Gen
human ... FGF2(2247)
Verwandte Kategorien
Allgemeine Beschreibung
Fibroblast growth factor 2 (FGF2), a canonical member, belongs to the fibroblast growth factor family.
Anwendung
Fibroblast Growth Factor-Basic Heparin Stabilized human has been used to culture Brown Norway rat yolk sac epithelial cells transformed with mouse sarcoma virus (BN/MSV). It has also been used in the preparation of serum-free mouse tubal epithelium growth medium (M-TE-GM) to culture primary tubal epithelium (TE) cells.
Biochem./physiol. Wirkung
Fibroblast growth factor 2 (FGF2) participates in tissue development and repair. It is also involved in embryonic development, angiogenesis, bone regeneration, stem cell self-renewal, and wound healing. The basic fibroblast growth factor (bFGF) plays a key role in the progression and maintenance of the nervous system. FGF2 binds to the FGF receptor (FGFR) and activates the extracellular signal-regulated kinase (ERK) pathway, which controls cellular behavior, using heparan sulfates (HS)/heparin as a cofactor. bFGF stimulates cell proliferation, differentiation, and migration in a variety of cell types. In cultured astrocytes from rat brain, recombinant human basic fibroblast growth factor (rhbFGF) may induce nerve growth factor (NGF) secretion. It is the heparin stabilized form of a natural mitogenic growth factor used in cell culture applications to study cell signaling and to promote fibroblast and endothelial cell growth and survival.
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Produkt-Nr.
Beschreibung
Preisangaben
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
Analysenzertifikate (COA)
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Artikel
Fibroblast growth factors in cell culture and various growth factors for your research
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