F6127

Fludrocortisonacetat

synthetic, ≥98%, glucocorticoid activity, powder

• Synonym(e): 9α-Fluor-11β,17α,21-trihydroxy-4-pregnen-3,20-dion-acetat, 9-Fluor-hydrocortison-acetat, 9-Fluorcortisol-acetat
• Empirische Formel (Hill-System): C₂₃H₃₁FO₆
• CAS-Nummer: 514-36-3
• Molekulargewicht: 422.49
• NACRES: NA.77
• PubChem Substance ID: 24894899
• UNSPSC Code: 12352200
• EC Number: 208-180-4
• MDL number: MFCD00864160
• Assay: ≥98%
• Form: powder

Eigenschaften

• Produktname: Fludrocortisonacetat, ≥98%
• biological source: synthetic
• Quality Segment: 100
• sterility: non-sterile
• assay: ≥98%
• form: powder
• solubility: acetone: 50 mg/mL, clear, colorless to light yellow
• shipped in: ambient
• storage temp.: room temp
• SMILES string: CC(=O)OCC(=O)[C@@]1(O)CC[C@H]2[C@@H]3CCC4=CC(=O)CC[C@]4(C)[C@@]3(F)[C@@H](O)C[C@]12C
• InChI: 1S/C23H31FO6/c1-13(25)30-12-19(28)22(29)9-7-16-17-5-4-14-10-15(26)6-8-20(14,2)23(17,24)18(27)11-21(16,22)3/h10,16-18,27,29H,4-9,11-12H2,1-3H3/t16-,17-,18-,20-,21-,22-,23-/m0/s1
• InChI key: SYWHXTATXSMDSB-GSLJADNHSA-N
• Gene Information: human ... NR3C2(4306)

Beschreibung

General description

Fludrocortisone acetate is secreted by adrenal cortex. It increases the reabsorption of sodium and secretion of potassium and hydrogen. Fludrocortisone is used to treat cerebral salt wasting syndrome and adrenal insufficiency. Fludrocortisone improves the sensitivity of blood vessels to catecholamines and increases the blood volume.

Biochem/physiol Actions

Fludrocortisone acetate is a synthetic corticosteroid with more mineralocorticoid than glucocorticoid activity.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P201 - P301 + P312 + P330 - P308 + P313
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable