F5178

Flavin-Containing Monooxygenase-5, Microsomes human

recombinant, expressed in baculovirus infected insect cells, buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)

• Synonym(e): FMO-5
• EC-Nummer: 1.14.13.8 (BRENDA, IUBMB)
• UNSPSC-Code: 12352204
• NACRES: NA.54

Eigenschaften

• Rekombinant: expressed in baculovirus infected insect cells
• Qualitätsniveau: 200
• Form: buffered aqueous solution (2.5 mg in 100 mM Potassium Phosphate Buffer)
• Spezifische Aktivität: ≥700 units/mg protein
• Mol-Gew.: 55-60 kDa
• Verpackung: vial of 2.5 mg
• UniProt-Hinterlegungsnummer: P49326
• Versandbedingung: dry ice
• Lagertemp.: −70°C
• Angaben zum Gen: human ... FMO5(2330)

Beschreibung

Anwendung

FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Biochem./physiol. Wirkung

FMO′s are responsible for catalyzing the oxygenation of a variety of xenobiotic and drug compounds including environmental pollutants and carcinogens, which demonstrate a nucleophilic nitrogen, sulfur, selenium, and phosphorous-containing moiety associated with their respective oxides. These enzymes are classified as Phase I or oxidative drug metabolism enzymes. FMO5 is the only FMO isoform expressed in both adult and fetal human liver.

Einheitendefinition

methyl p-tolyl sulfide oxidase activity: One unit will catalyze the production of 1.0 picomole of methyl p-tolyl sulfoxide.

Physikalische Form

Solution in 100 mM potassium phosphate buffer, pH 7.4.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable
• Persönliche Schutzausrüstung: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)