F4505

3-Fluor-DL-tyrosin

Name: 3-Fluor-<SC>DL</SC>-tyrosin
Brand: SIGMA
Price: 441 EUR

≥98%, suitable for ligand binding assays

Synonym(e):

3-fluoro-tyrosine

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F4505-500MG

€ 441,00

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Über diesen Artikel

Lineare Formel:

FC₆H₃-4-(OH)CH₂CH(NH₂)CO₂H

CAS-Nummer:

403-90-7

Molekulargewicht:

199.18

NACRES:

NA.26

PubChem Substance ID:

24894865

UNSPSC Code:

12352209

EC Number:

206-964-0

MDL number:

MFCD00063075

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Unterstützung erhalten

Produktname

3-Fluor-DL-tyrosin,

assay

≥98%

Quality Level

200

form

powder

technique(s)

ligand binding assay: suitable

color

white

mp

280 °C (dec.) (lit.)

storage temp.

2-8°C

SMILES string

NC(Cc1ccc(O)c(F)c1)C(O)=O

InChI

1S/C9H10FNO3/c10-6-3-5(1-2-8(6)12)4-7(11)9(13)14/h1-3,7,12H,4,11H2,(H,13,14)

InChI key

VIIAUOZUUGXERI-UHFFFAOYSA-N

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1 of 4

Dieser Artikel	D0629	L7002	A6751
Sigma-Aldrich F4505 m-Fluoro-DL-tyrosine	Sigma-Aldrich D0629 3,5-Diiodo-L-thyronine	Sigma-Aldrich L7002 L-Lysine p-nitroanilide dihydrobromide	Sigma-Aldrich A6751 N-Acetyl-L-tyrosine ethyl ester monohydrate
form powder	form powder	form powder	form powder
assay ≥98%	assay ≥99% (HPLC)	assay ≥98% (TLC)	assay ≥98%
technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable	technique(s) ligand binding assay: suitable
storage temp. 2-8°C	storage temp. −20°C	storage temp. 2-8°C	storage temp. −20°C
mp 280 °C (dec.) (lit.)	mp 255 °C	mp -	mp -
Quality Level 200	Quality Level 200	Quality Level 200	Quality Level 200

Biochem/physiol Actions

M-Fluorotyrosine (m-Fluoro-DL-tyrosine) may be substituted for tyrosine in the biosynthesis of proteins such as β-galactosidases (Escherichia coli), bacteriorhodopsin and intestinal microvillar enzymes, eg. aminopeptidase N, to study the effect of halogenated tryosines on the proteins properties.

pictograms

GHS07

signalword

Warning

hcodes

H302 + H312 + H332

pcodes

P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312

Hazard Classifications

Acute Tox. 4 Dermal - Acute Tox. 4 Inhalation - Acute Tox. 4 Oral

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

dust mask type N95 (US), Eyeshields, Gloves

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Fluorine NMR is a useful tool to probe protein folding, conformation and local topology owing to the sensitivity of the chemical shift to the local electrostatic environment. As an example we make use of (19)F NMR and 3-fluorotyrosine to evaluate

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Expressed protein ligation (EPL) allows semisynthesis of a target protein with site-specific incorporation of probes or unnatural amino acids at its N or C termini. Here, we describe the protocol that our lab has developed for incorporating fluorotyrosines (F(n)Ys) at

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