E2031

Eliprodil

≥98% (HPLC), powder

• Synonym(e): α-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL 820715
• Empirische Formel (Hill-System): C₂₀H₂₃ClFNO
• CAS-Nummer: 119431-25-3
• Molekulargewicht: 347.85
• NACRES: NA.77
• PubChem Substance ID: 24277709
• UNSPSC Code: 12352200
• MDL number: MFCD00866651
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• Quality Segment: 200
• assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 5 mg/mL, clear, H₂O: insoluble
• originator: Sanofi Aventis
• storage temp.: 2-8°C
• SMILES string: OC(CN1CCC(CC1)Cc2ccc(F)cc2)c3ccc(Cl)cc3
• InChI: 1S/C20H23ClFNO/c21-18-5-3-17(4-6-18)20(24)14-23-11-9-16(10-12-23)13-15-1-7-19(22)8-2-15/h1-8,16,20,24H,9-14H2
• InChI key: GGUSQTSTQSHJAH-UHFFFAOYSA-N
• Gene Information: human ... GRIN2B(2904) ; rat ... Adra1a(29412)

Beschreibung

Biochem/physiol Actions

NR2B selective NMDA glutamate receptor antagonist which appears to target the "polyamine site" on the NMDA receptor, setting it apart from other NR2B receptor antagonists. Possesses neuroprotective effects in models of ischemia, but prolongs the QT interval in patients; currently under investigation for acute and chronic pain.

NR2B selective NMDA glutamate receptor antagonist.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves