E0881

Elastatinal

Name: Elastatinal
Brand: SIGMA
Price: 141.1 EUR

powder

Synonym(e):

(2S)-2-[(4S)-2-Amino-1,4,5,6-tetrahydro4-pyrimidinyl]-N-[[[(1S)-1-carboxy-3-methylbutyl]amino]carbonyl]glycyl-N1-[(1S)-1-methyl-2-oxoethyl-L-glutamamide

Slide 1 of 2

Anmelden zur Ansicht der Organisations- und Vertragspreise.

Größe auswählen

5 MG

€ 141,10

10 MG

€ 287,00

25 MG

€ 595,00

€ 141,10

Listenpreis€ 166,00Sparen Sie 15%

Aktion nur im Web

Warenkorb auf Verfügbarkeit prüfen

Großbestellung anfragen

Über diesen Artikel

Empirische Formel (Hill-System):

C₂₁H₃₆N₈O₇

CAS-Nummer:

51798-45-9

Molekulargewicht:

512.56

MDL number:

MFCD00151180

UNSPSC Code:

12352202

PubChem Substance ID:

24894375

NACRES:

NA.77

EC Number:

257-426-7

Beilstein/REAXYS Number:

873543

Wichtige Dokumente

Gesamtdokumentation anzeigen

Fortfahren mit

Technischer Dienst

Benötigen Sie Hilfe? Unser Team von erfahrenen Wissenschaftlern ist für Sie da.

Unterstützung erhalten

Produktname

Elastatinal, microbial

SMILES string

[H]C(=O)[C@H](C)NC(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](NC(=O)N[C@@H](CC(C)C)C(O)=O)[C@]1([H])CCNC(=N)N1

InChI

1S/C21H36N8O7/c1-10(2)8-14(19(34)35)28-21(36)29-16(12-6-7-24-20(23)27-12)18(33)26-13(4-5-15(22)31)17(32)25-11(3)9-30/h9-14,16H,4-8H2,1-3H3,(H2,22,31)(H,25,32)(H,26,33)(H,34,35)(H3,23,24,27)(H2,28,29,36)/t11-,12-,13-,14-,16-/m0/s1

InChI key

IJWCGVPEDDQUDE-YGJAXBLXSA-N

biological source

microbial

form

powder

solubility

water: 20 mg/mL, clear, faintly yellow to yellow

storage temp.

−20°C

Quality Level

200

Ähnliche Artikel vergleichen

Vollständigen Vergleich anzeigen

Unterschiede anzeigen

1 of 4

Dieser Artikel	SML3263	SML2301	E9658
Sigma-Aldrich E0881 Elastatinal	Sigma-Aldrich SML3263 Edoxaban tosylate	Sigma-Aldrich SML2301 EpoY	Sigma-Aldrich E9658 Enalaprilat dihydrate
biological source microbial	biological source -	biological source -	biological source -
Quality Level 200	Quality Level 100	Quality Level -	Quality Level 100
form powder	form powder	form powder	form -
solubility water: 20 mg/mL, clear, faintly yellow to yellow	solubility DMSO: 2 mg/mL, clear	solubility DMSO: 2 mg/mL, clear	solubility H₂O: 14 mg/mL at 60 °C (warming for 5 minutes), DMSO: 64 mg/mL
storage temp. −20°C	storage temp. 2-8°C	storage temp. 2-8°C	storage temp. room temp

Biochem/physiol Actions

potenter, irreversibler Elastase-Inhibitor

Potent, irreversible elastase inhibitor. Elastatinal is a much stronger inhibitor of elastase from pancreas than from leucocytes.

Lagerklasse

11 - Combustible Solids

wgk

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)

Hier finden Sie alle aktuellen Versionen:

Analysenzertifikate (COA)

Lot/Batch Number

Die passende Version wird nicht angezeigt?

Wenn Sie eine bestimmte Version benötigen, können Sie anhand der Lot- oder Chargennummer nach einem spezifischen Zertifikat suchen.

Suche nach COA

Besitzen Sie dieses Produkt bereits?

In der Dokumentenbibliothek finden Sie die Dokumentation zu den Produkten, die Sie kürzlich erworben haben.

Die Dokumentenbibliothek aufrufen

Oral peptide drug delivery: polymer-inhibitor conjugates protecting insulin from enzymatic degradation in vitro.

M K Marschütz et al.

Biomaterials, 21(14), 1499-1507 (2000-06-29)

A drug-carrier matrix has been developed which protects embedded insulin from degradation by the luminally secreted serine-proteases trypsin (EC 3.4.21.4), chymotrypsin (EC 3.4.21.1) and elastase (EC 3.4.21.36) in vitro. Increasing amounts of the Bowman-Birk inhibitor (BBI) and elastatinal, respectively, were

Reduction of active elastase concentration by means of immobilized inhibitors: a novel therapeutic approach.

Valentina Grano et al.

Biotechnology progress, 20(3), 968-974 (2004-06-05)

The inhibitory power of three different active Nylon membranes, separately loaded with three different protease inhibitors, was studied with the aim of reducing the increased elastase concentration occurring during hemodialysis or extracorporeal blood circulation in patients undergoing cardiopulmonary bypass. Chemical

Proteolytic inactivation of human leukocyte elastase.

R L Stein et al.

Experientia, 41(5), 638-640 (1985-05-15)

Human leukocyte elastase can be proteolytically inactivated by bovine pancreatic trypsin. Neither porcine pancreatic elastase nor bovine pancreatic chymotrypsin causes inactivation of leukocyte elastase, nor are trypsin, pancreatic elastase, or chymotrypsin themselves susceptible to proteolysis. The trypsin-catalyzed inactivation of leukocyte

Superoxide dismutase mimetics inhibit neutrophil-mediated human aortic endothelial cell injury in vitro.

M M Hardy et al.

The Journal of biological chemistry, 269(28), 18535-18540 (1994-07-15)

In this study, we evaluated the ability of low molecular weight manganese-based superoxide dismutase mimetics to attenuate neutrophil-mediated oxygen radical damage to human aortic endothelial cells in vitro. Human neutrophils, when exposed to tumor necrosis factor-alpha and the complement compound

Elastatinal and leupeptin: effects on u.v.-induced mutation and sister-chromatid exchanges in Chinese hamster cells.

P Paul et al.

Carcinogenesis, 2(4), 255-259 (1981-01-01)

Microbial protease inhibitors elastatinal and leupeptin were tested for cytotoxicity and for effects on spontaneous and u.v.-induced 6-thioguanine-resistant (6TGr) mutation and sister-chromatid exchange (SCE) in V79 Chinese hamster cells. Continuous treatment with elastatinal exhibited marked cytotoxicity, while leupeptin was almost

Alle zugehörigen Dokumente anzeigen

Questions

Reviews

No rating value

Active Filters

Unser Team von Wissenschaftlern verfügt über Erfahrung in allen Forschungsbereichen einschließlich Life Science, Materialwissenschaften, chemischer Synthese, Chromatographie, Analytik und vielen mehr..

Setzen Sie sich mit dem technischen Dienst in Verbindung

Elastatinal