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Dokumente

D6149

Sigma-Aldrich

1-Desoxy-1-Morpholino-D-Fructose

≥98% (TLC)

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About This Item

Empirische Formel (Hill-System):
C10H19NO6
CAS-Nummer:
6291-16-3
Molekulargewicht:
249.26
Beilstein:
19582
MDL-Nummer:
MFCD00166980
UNSPSC-Code:
12352201
PubChem Substanz-ID:
24894004
NACRES:
NA.25

Qualitätsniveau

200

Assay

≥98% (TLC)

Form

powder

Methode(n)

thin layer chromatography (TLC): suitable

Farbe

white to off-white

mp (Schmelzpunkt)

147 °C

Löslichkeit

methanol: 19.60-20.40 mg/mL, clear, colorless to faintly yellow

Lagertemp.

−20°C

SMILES String

OC[C@@H](O)[C@@H](O)[C@H](O)C(=O)CN1CCOCC1

InChI

1S/C10H19NO6/c12-6-8(14)10(16)9(15)7(13)5-11-1-3-17-4-2-11/h8-10,12,14-16H,1-6H2/t8-,9-,10-/m1/s1

InChIKey

JPANQHVKLYKLEB-OPRDCNLKSA-N

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Verwandte Kategorien

Anwendung

DMF (1-Deoxy-1-morpholino-D-fructose), an analog of the 1-desoxy-1-amino-fructose radical found in glycated proteins, has been used in the development of glycation assays.

Sonstige Hinweise

To gain a comprehensive understanding of our extensive range of Monosaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)

Analysenzertifikate (COA)

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R N Johnson et al.
Clinical chemistry, 32(2), 368-370 (1986-02-01)
We investigated the ability of the fructosamine assay to detect glycation of serum proteins. We incubated both whole human serum and serum protein fractions in vitro with [14C]glucose, and analyzed for reducing activity and for uptake of 14C by protein.
J E Howey et al.
Clinical chemistry, 33(2 Pt 1), 269-272 (1987-02-01)
Methodological problems with the assay of fructosamine in serum--standardization, matrix effects, and dependence on buffer pH--have been minimized with a method involving colorimetric assay of each specimen and subsequent re-assay after standard addition of 1-deoxy-1-morpholinofructose. Absorbance at optimum wavelength of
Yan Wei et al.
BMC cell biology, 10, 10-10 (2009-02-17)
D-ribose in cells and human serum participates in glycation of proteins resulting in advanced glycation end products (AGEs) that affect cell metabolism and induce cell death. However, the mechanism by which D-ribose-glycated proteins induce cell death is still unclear. Here
Kenia Vázquez-Sánchez et al.
Food chemistry, 261, 253-259 (2018-05-10)
Antioxidant dietary fiber extracted from spent coffee grounds (FSCG) was evaluated as a potential functional food ingredient when incorporated in a food model (biscuits), and digested in vitro under simulated human gastrointestinal conditions. FSCG added to biscuits increased its total
G Delpierre et al.
The Biochemical journal, 352 Pt 3, 835-839 (2000-12-06)
Intact human erythrocytes catalyse the conversion of fructose into fructose 3-phosphate with an apparent K(m) of 30 mM [Petersen, Kappler, Szwergold and Brown (1992) Biochem. J. 284, 363-366]. The physiological significance of this process is still unknown. In the present
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