C6143

Chlorhexidine diacetate salt hydrate

bis(biguanide) antimicrobial

• Synonym(e): 1,6-Bis(N⁵-[p-chlorophenyl]-N¹-biguanido)hexane; 1,1′-Hexamethylenebis(5-[p-chlorophenyl]biguanide)
• Empirische Formel (Hill-System): C₂₂H₃₀Cl₂N₁₀ · 2C₂H₄O₂ · xH₂O
• CAS-Nummer: 206986-79-0
• Molekulargewicht: 625.55 (anhydrous basis)
• NACRES: NA.85
• PubChem Substance ID: 24892838
• UNSPSC Code: 51102829
• EC Number: 200-302-4
• MDL number: MFCD00012532

Eigenschaften

• Quality Segment: 200
• form: powder
• CMC: 0.01% (25°C)(w/v)
• solubility: ethanol: 50 mg/mL
• antibiotic activity spectrum: Gram-negative bacteria, Gram-positive bacteria
• mode of action: cell membrane | interferes
• storage temp.: room temp
• SMILES string: ClC1=CC=C(NC(NC(NCCCCCCNC(NC(NC2=CC=C(Cl)C=C2)=N)=N)=N)=N)C=C1.OC(C)=O.OC(C)=O
• InChI: 1S/C22H30Cl2N10.2C2H4O2/c23-15-5-9-17(10-6-15)31-21(27)33-19(25)29-13-3-1-2-4-14-30-20(26)34-22(28)32-18-11-7-16(24)8-12-18;2*1-2(3)4/h5-12H,1-4,13-14H2,(H5,25,27,29,31,33)(H5,26,28,30,32,34);2*1H3,(H,3,4)
• InChI key: WDRFFJWBUDTUCA-UHFFFAOYSA-N

Beschreibung

Application

Used to study mechanism of membrane dysruption by bis(biguanide) molecules.

Biochem/physiol Actions

Chlorhexidine is a cationic broad-spectrum antimicrobial agent belonging to the bis(biguanide) family. Its mechanism of action involves destabilization of the outer bacterial membrane. It is effective against both Gram-positive and Gram-negative bacteria. Chlorhexidine is used primarily as a topical antiseptic/disinfectant in wound healing, at catheterization sites, in various dental applications and in surgical scrubs.

Other Notes

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.

Disclaimer

The product is not intended for use as a biocide under global biocide regulations, including but not limited to US EPA′s Federal Insecticide Fungicide and Rodenticide Act, European Biocidal Products Regulation, Canada’s Pest Management Regulatory Agency, Turkey’s Biocidal Products Regulation, Korea’s Consumer Chemical Products and Biocide Safety Management Act (K-BPR) and others.

Sicherheitshinweise

• pictograms: GHS08,GHS07,GHS09
• signalword: Warning
• hcodes: H302,H315,H319,H371,H410
• pcodes: P260 - P273 - P301 + P312 - P302 + P352 - P305 + P351 + P338 - P308 + P311
• Hazard Classifications: Acute Tox. 4 Oral - Aquatic Acute 1 - Aquatic Chronic 1 - Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 2
• target_organs: Liver,Teeth
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)