C3657

Human Collagen Type IX

from human placenta, powder, suitable for detection assays

• CAS-Nummer: 9007-34-5
• UNSPSC Code: 12352202
• NACRES: NA.32
• EC Number: 232-697-4
• MDL number: MFCD00130825
• Form: powder
• Biological source: human placenta

Eigenschaften

• Produktname: Kollagen aus menschlicher Placenta, Bornstein and Traub Type V (Sigma Type IX), powder
• biological source: human placenta
• form: powder
• impurities: HIV, hepatitis B and hepatitis C, none detected
• solubility: aqueous acid: soluble
• UniProt accession no.: P20908
• application(s): detection
• storage temp.: 2-8°C
• Gene Information: human ... COL5A1(1289)

Beschreibung

Preparation Note

This product was prepared by a modification of the pepsin extraction and salt fractionation method of Niyibizi, C., et al., J. Biol. Chem., 259, 14170 (1984). It is an acid soluble collagen that can be dissolved in water with acetic acid added to pH 3.0 (5 mg/mL), yielding an opalescent, colorless solution.

Analysis Note

An SDS polyacrylamide gel electrophoresis test run under reducing conditions consistent with basement membrane collagen yields three major bands.

Other Notes

Kollagen wird in eine Reihe an strukturell und genetisch verschiedenen Typen unterteilt. Wir nutzen die Nomenklatur, die von Bornstein und Traub vorgeschlagen wurde. Achten Sie darauf, dass Sie die Typenbezeichnungen von Sigma nicht mit anerkannten Typenklassifizierungen von Kollagen verwechseln.

All collagen molecules are composed of three polypeptide chains arranged in a triple helical conformation, with a primary structure that is mostly a repeating motif with glycine in every third position and proline or 4-hydroxyproline frequently preceding the glycine residue.

Disclaimer

This product should be stored desiccated at -20°C, and will retain activity in these conditions for 3 years.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)