C0742

CKI-7 dihydrochloride

≥98% (HPLC), solid, CK1 inhibitor

• Synonym(e): N-(2-Aminoethyl)-5-chloroisoquinoline-8-sulphonamide dihydrochloride
• Empirische Formel (Hill-System): C₁₁H₁₂ClN₃O₂S · 2HCl
• CAS-Nummer: 1177141-67-1
• Molekulargewicht: 358.67
• UNSPSC Code: 12352200
• PubChem Substance ID: 24724430
• NACRES: NA.77
• MDL number: MFCD00897689
• Assay: ≥98% (HPLC)
• Form: solid
• Storage condition: desiccated

Eigenschaften

• Produktname: CKI-7 dihydrochloride, ≥98% (HPLC), solid
• assay: ≥98% (HPLC)
• form: solid
• storage condition: desiccated
• color: white to light tan
• solubility: H₂O: >5 mg/mL
• storage temp.: −20°C
• SMILES string: Cl[H].Cl[H].NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
• InChI: 1S/C11H12ClN3O2S.2ClH/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10;;/h1-3,5,7,15H,4,6,13H2;2*1H
• InChI key: JUAVTXYOCISSSL-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1.

CKI-7 is a CK1 inhibitor; also inhibits SGK, S6K1 and MSK1. CKI-7 inhibits SGK as potently as CK1. IC₅₀ = 6 μM.

Disclaimer

Material is hygroscopic

Sicherheitshinweise

• pictograms: GHS06
• signalword: Danger
• hcodes: H301
• pcodes: P264 - P270 - P301 + P310 - P405 - P501
• Hazard Classifications: Acute Tox. 3 Oral
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges