C0399

Cromolyn Natriumsalz

≥95%, Mast cell stabilizer, powder

• Synonym(e): Cromoglycate, Cromoglycic acid
• Lineare Formel: C₂₃H₁₄O₁₁Na₂
• CAS-Nummer: 15826-37-6
• Molekulargewicht: 512.33
• NACRES: NA.77
• PubChem Substance ID: 24892251
• UNSPSC Code: 12352200
• EC Number: 239-926-7
• MDL number: MFCD00057744
• Assay: ≥95%
• Form: powder

Eigenschaften

• Produktname: Cromolyn Natriumsalz, ≥95%
• Quality Segment: 200
• assay: ≥95%
• form: powder
• originator: Sanofi Aventis
• SMILES string: [Na].OC(COc1cccc2OC(=CC(=O)c12)C(O)=O)COc3cccc4OC(=CC(=O)c34)C(O)=O
• InChI: 1S/C23H16O11.Na.H/c24-11(9-31-14-3-1-5-16-20(14)12(25)7-18(33-16)22(27)28)10-32-15-4-2-6-17-21(15)13(26)8-19(34-17)23(29)30;;/h1-8,11,24H,9-10H2,(H,27,28)(H,29,30);;
• InChI key: UXMUBZWVLQEMRB-UHFFFAOYSA-N

Beschreibung

General description

Cromolyn sodium is a mast stabilizer, which is used to treat allergies. It is a bischromone and functions as a non-steroidal anti-inflammatory drug. It inhibits the release of histamines from mast cells.

Application

Cromolyn sodium salt has been used to block mast cell activation and to inhibit histamine secretion from rodent peritoneal mast cells. It has also been used to stabilize mast cells.

Biochem/physiol Actions

Cromolyn blocks the release of histamine and other pro-inflammatory mediators from mast cells.

Features and Benefits

This compound was developed by Sanofi Aventis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H315,H319,H335
• pcodes: P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338
• Hazard Classifications: Eye Irrit. 2 - Skin Irrit. 2 - STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: dust mask type N95 (US), Eyeshields, Gloves