B9688

Pizotifen

≥98% (HPLC)

• Synonym(e): Pizotifen, Pizotyline; 4-(9,10-Dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methylpiperidine
• Empirische Formel (Hill-System): C₁₉H₂₁NS
• CAS-Nummer: 15574-96-6
• Molekulargewicht: 295.44
• NACRES: NA.77
• PubChem Substance ID: 329773323
• UNSPSC Code: 12352200
• EC Number: 239-632-9
• MDL number: MFCD00864192
• Assay: ≥98% (HPLC)
• Form: powder

Eigenschaften

• assay: ≥98% (HPLC)
• form: powder
• solubility: DMSO: ≥8 mg/mL
• originator: Novartis
• storage temp.: room temp
• SMILES string: CN1CCC(\CC1)=C2\c3ccccc3CCc4sccc24
• InChI: 1S/C19H21NS/c1-20-11-8-15(9-12-20)19-16-5-3-2-4-14(16)6-7-18-17(19)10-13-21-18/h2-5,10,13H,6-9,11-12H2,1H3
• InChI key: FIADGNVRKBPQEU-UHFFFAOYSA-N

Beschreibung

Biochem/physiol Actions

Pizotifen is a Serotonin antagonist used for prophylaxis of migraine

Pizotifen is a serotonin antagonist acting mainly at the 5-HT1, 5-HT2A and 5HT2C receptors with some antihistamine activity. It is used for the prevention of vascular headache including migraine and cluster headache.

Features and Benefits

This compound was developed by Novartis. To browse the list of other pharma-developed compounds and Approved Drugs/Drug Candidates, click here.

Sicherheitshinweise

• pictograms: GHS08,GHS07
• signalword: Warning
• hcodes: H302,H361
• pcodes: P202 - P264 - P280 - P301 + P312 - P308 + P313 - P405
• Hazard Classifications: Acute Tox. 4 Oral - Repr. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable