The 100 mg package size has a volume of 500 ul. This product is prepared at 200 mg/mL in 0.5 mL of 0.15 M NaCl, 0.1 M sodium phosphate, pH 7.2.
B8556
Hemocyanin from mollusk
buffered aqueous solution
Synonym(e):
Blue Carrier®
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Form:
buffered aqueous solution
Biological source:
Concholepas sp. (Concholepas concholepas )
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Unterstützung erhaltenbiological source
Concholepas sp. (Concholepas concholepas )
form
buffered aqueous solution
technique(s)
bioconjugation: suitable
storage temp.
2-8°C
Quality Level
1 of 4
Dieser Artikel | |||
|---|---|---|---|
| biological source Concholepas sp. (Concholepas concholepas ) | biological source Megathura crenulata | biological source Megathura crenulata | biological source - |
| technique(s) bioconjugation: suitable | technique(s) ELISA: suitable | technique(s) ELISA: suitable | technique(s) - |
| form buffered aqueous solution | form PBS solution | form powder | form liquid |
| storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 200 | Quality Level 300 | Quality Level 300 | Quality Level 100 |
Application
Blue Carrier is an oxygen-carrying protein isolated from the hemolymph of the mollusk Concholepas concholepas. It is highly immunogenic, useful as a carrier protein for the production of antibodies to small molecules. An example of the protocol is given in reference to production of antibodies to gizzerosine.[1]
Hemocyanin is a carrier protein used in antibody production. It has been used to promote antibody production against haptins and peptides, in therepy for bladder carcinoma, and has a component in vaccines for cancer.
Biochem/physiol Actions
Highly soluble carrier protein used in antibody production
Physical form
100 mg in 0.5 mL of 0.15 M NaCl, 0.1 M sodium phosphate, pH 7.2
Legal Information
Blue Carrier is a registered trademark of Biosonda S.A.
Lagerklasse
10 - Combustible liquids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)
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M I Becker et al.
Hybridoma, 17(4), 373-381 (1998-10-28)
This study is the first report of the development of monoclonal antibodies (MAbs) against gizzerosine (GZ), one of the causative agents of black vomit, a serious poultry disease. Balb/c mice were immunized with different GZ conjugates; the most immunogenic conjugate
Harold Oliva et al.
Hybridoma and hybridomics, 21(5), 365-374 (2002-12-10)
We studied the reactivity of mouse monoclonal antibodies (MAbs) against the hemocyanin from the Chilean marine gastropod Concholepas concholepas (CCH). This protein has been successfully used as a carrier to produce antibodies to haptens and peptides. All MAbs (13) belonging
Enhanced structural stability of Concholepas hemocyanin increases its immunogenicity and maintains its non-specific immunostimulatory effects.
Arancibia S., et al.
European Journal of Immunology (2011)
Bruno Moltedo et al.
The Journal of urology, 176(6 Pt 1), 2690-2695 (2006-11-07)
We determined the antitumor properties of a newly available hemocyanin obtained from the Chilean gastropod Concholepas concholepas (Biosonda Corp., Santiago, Chile) in a syngeneic heterotopic mouse bladder carcinoma model. Since keyhole limpet hemocyanin (Pierce, Rockford, Illinois) is used increasingly in
Anaphylaxis caused by hemocyanin contained in shrimp cephalothorax.
Daiana Guillen et al.
Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 113(6), 674-675 (2014-10-14)
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