B5438

Balsalazide disodium salt hydrate

• Synonym(e): 5-[4-(2-Carboxyethylcarbamoyl)phenylazo]salicylic acid disodium salt hydrate
• Empirische Formel (Hill-System): C₁₇H₁₃N₃Na₂O₆ · xH₂O
• CAS-Nummer: 213594-60-6
• Molekulargewicht: 401.28 (anhydrous basis)
• NACRES: NA.25
• PubChem Substance ID: 329773261
• UNSPSC Code: 12352100
• MDL number: MFCD18632541

Eigenschaften

• assay: ≥99% (HPLC)
• form: powder
• storage temp.: 2-8°C
• SMILES string: O.[Na+].[Na+].Oc1ccc(cc1C([O-])=O)\N=N\c2ccc(cc2)C(=O)NCCC([O-])=O
• InChI: 1S/C17H15N3O6.2Na.H2O/c21-14-6-5-12(9-13(14)17(25)26)20-19-11-3-1-10(2-4-11)16(24)18-8-7-15(22)23;;;/h1-6,9,21H,7-8H2,(H,18,24)(H,22,23)(H,25,26);;;1H2/q;2*+1;/p-2/b20-19+;;;
• InChI key: ZZZXQZHSFPVNCR-HVARVCSCSA-L

Beschreibung

Biochem/physiol Actions

Balsalazide has antioxidative and anti-inflammatory properties. It inhibits superoxide production and was found to scavenge hypochlorite radicals. Balsalazide was shown to inhibit lipid peroxidation in rat intestinal mucosa. It was also shown to inhibit azoxymethane-induced colon carcinogenesis. In vivo, basalazide is cleaved through azoreduction to produce 4-aminobenzoyl-β-alanine, an inert carrier moiety, and 5-aminosalicylic acid (5-ASA).

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable