B0311

Bmx Active human

recombinant, expressed in E. coli, ≥85% (SDS-PAGE), buffered aqueous glycerol solution

• Synonym(e): Bone Marrow Kinase X-Linked
• UNSPSC Code: 12352200
• NACRES: NA.32
• MDL number: MFCD07370635
• Specific activity: ≥10 units/mg protein
• Assay: ≥85% (SDS-PAGE)
• Recombinant: expressed in E. coli

Eigenschaften

• recombinant: expressed in E. coli
• Quality Segment: 200
• assay: ≥85% (SDS-PAGE)
• form: buffered aqueous glycerol solution
• specific activity: ≥10 units/mg protein
• mol wt: ~110 kDa
• UniProt accession no.: P51813
• shipped in: dry ice
• storage temp.: −70°C
• Gene Information: human ... BMX(660)

Beschreibung

Biochem/physiol Actions

The BMX gene encodes a novel non-receptor tyrosine kinase, which may play a role in the growth and differentiation of hematopoietic cells. Bmx induces the activation of the Stat-signaling pathway.

Physical form

Solution of 50 μL in 50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 0.25 mM DTT, 0.1 mM EGTA, and 30% glycerol.

Other Notes

Kinase activity is measured as the molar amount of phosphate incorporated into Poly Glu-Tyr substrate per minute per mg protein at 30 °C using a final concentration of 50 μM [³²P]-ATP.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, multi-purpose combination respirator cartridge (US)