The product impurities are not identified or quantified. Please see the product specification sheet:
https://www.sigmaaldrich.com/specification-sheets/457/256/A9043-BULK________SIGMA____.pdf.
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A9043
S-Acetylthioglykolsäure-N-hydroxysuccinimid-Ester
≥95% (TLC), powder
Synonym(e):
(Acetylthio)-essigsäure-N-succinimidylester, N-Succinimidyl-S-acetylthioglykolat, S-Acetylthioglycolsäure-NHS-ester
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10 MG
€ 41,50
50 MG
€ 88,60
100 MG
€ 147,00
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10 MG
€ 41,50
50 MG
€ 88,60
100 MG
€ 147,00
About This Item
Empirische Formel (Hill-System):
C8H9NO5S
CAS-Nummer:
Molekulargewicht:
231.23
Beilstein:
7815491
MDL-Nummer:
UNSPSC-Code:
12352100
PubChem Substanz-ID:
NACRES:
NA.22
Empfohlene Produkte
Qualitätsniveau
Assay
≥95% (TLC)
Form
powder
Löslichkeit
acetonitrile: 50 mg/mL
DMF: soluble
Lagertemp.
−20°C
SMILES String
CC(=O)SCC(=O)ON1C(=O)CCC1=O
InChI
1S/C8H9NO5S/c1-5(10)15-4-8(13)14-9-6(11)2-3-7(9)12/h2-4H2,1H3
InChIKey
FLCQLSRLQIPNLM-UHFFFAOYSA-N
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Anwendung
Thiolating reagent for primary amines; thiol can be deprotected under mild conditions. Typically, couples initially to a molecule containing primary amine by amide bond buffered at pH 7.5. Deprotection may be accomplished with 0.05 M hydroxylamine at neutral pH. Useful for preparation of enzyme immunoconjugates and hapten carrier molecule conjugates.
Sonstige Hinweise
Note that the ester couples very efficiently to primary amines compared to other thiolating reagents. In addition, this reagent will neutralize original amine positive charge.
Lagerklassenschlüssel
11 - Combustible Solids
WGK
WGK 3
Flammpunkt (°F)
Not applicable
Flammpunkt (°C)
Not applicable
Persönliche Schutzausrüstung
Eyeshields, Gloves, type N95 (US)
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Hello, Could you tell me the percentage of impurities and define specifically which impurities we can find in this reagent ? Thank you,
1 answer-
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