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62335
Lipoprotein-Lipase aus Pseudomonas sp.
lyophilized, powder, ≥1200 U/mg
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| Ihnen/SKU | Verfügbarkeit | Preis |
|---|---|---|
10 mg | Warenkorb auf Verfügbarkeit prüfen | € 106,00 |
50 mg | Warenkorb auf Verfügbarkeit prüfen | € 386,00 |
Über diesen Artikel
CAS-Nummer:
UNSPSC Code:
12352204
NACRES:
NA.54
EC Number:
232-669-1
MDL number:
Specific activity:
≥1200 U/mg
Biological source:
bacterial (Pseudomonas spp.)
Technischer Dienst
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Unterstützung erhaltenbiological source
bacterial (Pseudomonas spp.)
Quality Segment
form
powder
quality
lyophilized
specific activity
≥1200 U/mg
storage temp.
−20°C
General description
Lipoprotein Lipase (LPL) is majorly secreted by myocytes and adipocytes in humans and is crucial for triglyceride homeostatis. Mutations in the catalytic domain of LPL impairs its interaction with glycosylphosphatidylinositol anchored high density lipoprotein binding protein 1 (GPIHBP1). The N-terminal catalytic domain is essential for lipolysis. The C-terminal is crucial for binding lipoproteins. Altered LPL levels may play role in the pathogenesis of atherosclerosis, coronary heart disease and chronic lymphocytic leukemia.
Application
Lipoprotein Lipase from Pseudomonas sp. has been used in the enzymatic erosion studies in gamma irradiated poly(trimethylene carbonate) (PTMC) films.
Biochem/physiol Actions
Lipoprotein lipase belongs to the family of triglyceride lipases. It hydrolyses triglycerides in triglyceride-rich ApoB-containing lipoproteins.
Malic dehydrogenase catalyzes the dehydrogenation of L-malate by NAD+.[1]
Other Notes
1 U entspricht der Enzymmenge, die 1 μmol Ölsäure pro Minute bei pH 8.0 und 40°C freisetzt (Triolein, Fluka®-Nr. 62314 als Substrat)
Preparation of aldol acceptors (R)- and (S)-3-azido-2-hydroxypropanal via lipase-catalyzed resolution of the racemic acetal precursor; Effect of enzyme form on its properties in toluene.
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Dieser Artikel | |||
|---|---|---|---|
| specific activity ≥1200 U/mg | specific activity ≥50,000 units/mg solid | specific activity ≥15 units/mg solid | specific activity ≥30 U/mg |
| biological source bacterial (Pseudomonas spp.) | biological source Burkholderia spp. | biological source - | biological source bacterial (Pseudomonas cepacia) |
| form powder | form lyophilized powder | form lyophilized powder | form powder |
| storage temp. −20°C | storage temp. −20°C | storage temp. 2-8°C | storage temp. 2-8°C |
| Quality Level 100 | Quality Level 200 | Quality Level 200 | Quality Level 100 |
| quality lyophilized | quality - | quality - | quality - |
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Lagerklasse
11 - Combustible Solids
wgk
WGK 3
flash_point_f
Not applicable
flash_point_c
Not applicable
ppe
Eyeshields, Gloves, type N95 (US)
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