44213

Thromboplastin aus Kaninchen

• Synonym(e): Thromboplastin aus Kaninchenhirn, Faktor III, Thrombokinase
• CAS-Nummer: 72162-96-0
• UNSPSC Code: 12352202
• EC Number: 276-433-6
• NACRES: NA.25
• MDL number: MFCD00148638
• Form: lyophilized solid
• Biological source: rabbit

Eigenschaften

• biological source: rabbit
• form: lyophilized solid
• UniProt accession no.: P24055
• storage temp.: 2-8°C
• Gene Information: rabbit ... F3(100009127)

Beschreibung

Application

Thromboplastin from rabbit has been used:

• as a standard in tissue factor procoagulant activity assay (TF-PCA)[1]
• in pulmonary embolism assay[2]
• as a positive control in clotting assay using human plasma[3]

Biochem/physiol Actions

Thromboplastin (Tissue factor) is a transmembrane protein, the chief in vivo activator of blood coagulation that leads to thrombin generation and fibrin deposition. It is also important in the activation of the coagulation protease cascade and is involved in the lethality of sepsis.[4], [5]

Thromboplastin from rabbit might be used to produce disseminated intravascular coagulation (DIC) in animal models.[6]

Packaging

Ein Vial enthält 3-4 mg Thromboplastin.

Preparation Note

reconstitute the content of 1 vial in 4 ml 10 mm CaCl₂

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H334
• pcodes: P261 - P284 - P501
• Hazard Classifications: Resp. Sens. 1
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 1
• ppe: Eyeshields, Gloves, type N95 (US)