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Merck

40227

Sigma-Aldrich

6-Dodecanoyl-N,N-dimethyl-2-naphthylamin

suitable for fluorescence, ≥97.0% (HPLC)

Synonym(e):

2-(Dimethylamino)-6-dodecanoyl-naphthalin, N,N-Dimethyl-6-dodecanoyl-2-naphthylamin, Laurdan

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About This Item

Empirische Formel (Hill-System):
C24H35NO
CAS-Nummer:
Molekulargewicht:
353.54
Beilstein:
7379104
MDL-Nummer:
UNSPSC-Code:
12352116
PubChem Substanz-ID:
NACRES:
NA.32

Assay

≥97.0% (HPLC)

mp (Schmelzpunkt)

88 °C (lit.)

Löslichkeit

DMF: soluble
acetonitrile: soluble
methanol: soluble

Fluoreszenz

λex 366 nm; λem 497 nm in methanol

Eignung

suitable for fluorescence

SMILES String

CCCCCCCCCCCC(=O)c1ccc2cc(ccc2c1)N(C)C

InChI

1S/C24H35NO/c1-4-5-6-7-8-9-10-11-12-13-24(26)22-15-14-21-19-23(25(2)3)17-16-20(21)18-22/h14-19H,4-13H2,1-3H3

InChIKey

JHDGGIDITFLRJY-UHFFFAOYSA-N

Verwandte Kategorien

Anwendung

6-Dodecanoyl-N,N-dimethyl-2-naphthylamine (Laurdan) is a fluorescent probe used to study membrane structure, order and dynamic processes such as fluidity.

Verpackung

Bottomless glass bottle. Contents are inside inserted fused cone.

Sonstige Hinweise

Fluoreszierende Membran-Sonde

Lagerklassenschlüssel

11 - Combustible Solids

WGK

WGK 3

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Persönliche Schutzausrüstung

Eyeshields, Gloves, type N95 (US)


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Scientific reports, 6, 19249-19249 (2016-01-19)
Recent studies have shown that pharmacological increases in HDL cholesterol concentrations do not necessarily translate into clinical benefits for patients, raising concerns about its predictive value for cardiovascular events. Here we hypothesize that the size-modulated lipid distribution within HDL particles
Simmon Hofstetter et al.
Journal of microbiological methods, 91(1), 93-100 (2012-08-14)
A method for measuring the fluidity of inner membranes of populations of endospores of Clostridium spp. with a fluorescent dye was developed. Cells of Clostridium beijerinckii ATCC 8260 and Clostridium sporogenes ATCC 7955 were allowed to sporulate in the presence
Keita Hayashi et al.
Colloids and surfaces. B, Biointerfaces, 87(1), 28-35 (2011-05-31)
The surface properties of Span 80 vesicles at various cholesterol contents, together with those of various liposomes, were characterized by using fluorescence probes. The membrane fluidity of the Span 80 vesicles was measured by 1,6-diphenyl-1.3.5-hexatriene (DPH) and trimethlyammonium-DPH (TMA-DPH), and
Jelena Dinic et al.
Biochimica et biophysica acta, 1828(3), 1102-1111 (2012-12-19)
The relationship between ordered plasma membrane nanodomains, known as lipid rafts, and actin filaments is the focus of this study. Plasma membrane order was followed in live cells at 37°C using laurdan and di-4-ANEPPDHQ to report on lipid packing. Disrupting

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