252-05N

Human Umbilical Artery Smooth Muscle Cells: HUASMC, neonatal

• NACRES: NA.81
• UNSPSC Code: 41106514
• Biological source: human umbilicus (normal arteries)
• Growth mode: Adherent
• Morphology: smooth muscle
• Relevant disease(s): diabetes; stroke; cardiovascular diseases

Eigenschaften

• biological source: human umbilicus (normal arteries)
• packaging: pkg of 500,000 cells
• manufacturer/tradename: Cell Applications, Inc
• growth mode: Adherent
• karyotype: 2n = 46
• morphology: smooth muscle
• technique(s): cell culture | mammalian: suitable
• relevant disease(s): diabetes; stroke; cardiovascular diseases
• shipped in: dry ice
• storage temp.: −196°C

Beschreibung

General description

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HUASMC has been used to study effects of snake venom on smooth muscle cells (Mora, 2008); secretion mechanism of the (pro)renin receptor (Yoshikawa, 2011) and the role of proteasomes (Martin, 2014) in the development of cardiovascular diseases; and to develop novel material surfaces to inhibit smooth muscle cell proliferation at the same time allowing endothelial cells adhesion and proliferation in order to reduce risk associated with vascular implants (Kanie, 2012). Characterization: positive for smooth muscle cell specific alpha-actin expression.

Application

vascular function, tissue engineering, pharmacology of vascular tissue

Biochem/physiol Actions

Artery

Preparation Note

• 2nd passage, >500,000 cells in Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO
• Can be cultured at least 16 doublings

Please refer to the HUASMC Culture Protocol.

Other Notes

Smooth Muscle Cell Basal Medium containing 10% FBS & 10% DMSO

Disclaimer

RESEARCH USE ONLY. This product is regulated in France when intended to be used for scientific purposes, including for import and export activities (Article L 1211-1 paragraph 2 of the Public Health Code). The purchaser (i.e. enduser) is required to obtain an import authorization from the France Ministry of Research referred in the Article L1245-5-1 II. of Public Health Code. By ordering this product, you are confirming that you have obtained the proper import authorization.

Sicherheitshinweise

• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable