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Merck

09963

(Hydroxypropyl)methylcellulose

Synonym(e):

2-Hydroxypropyl methyl cellulose ether

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Über diesen Artikel

CAS-Nummer:
UNSPSC Code:
12352201
NACRES:
NA.25
MDL number:

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Unterstützung erhalten

form

powder

Quality Level

composition

hydroxylpropoxyl content, ~9%

color

faint beige

viscosity

~15 mPa.s, 2 % in H2O(25 °C)

solubility

water: 100 mg/10 mL, clear, colorless

storage temp.

room temp

SMILES string

O3[C@H]([C@@H]([C@H]([C@@H]([C@H]3COCC(O)C)OCC(O)C)OCC(O)C)OCC(O)C)O[C@@H]4[C@H](O[C@H]([C@@H]([C@H]4OCC(O)C)OCC(O)C)OCC(O)C)COCC(O)C.O1[C@H]([C@@H]([C@H]([C@@H]([C@H]1COC)OC)OC)OC)O[C@@H]2[C@H](O[C@H]([C@@H]([C@H]2OC)OC)OC)COC

InChI

1S/C36H70O19.C20H38O11/c1-19(37)9-45-17-27-29(47-11-21(3)39)31(48-12-22(4)40)34(51-15-25(7)43)36(54-27)55-30-28(18-46-10-20(2)38)53-35(52-16-26(8)44)33(50-14-24(6)42)32(30)49-13-23(5)41;1-21-9-11-13(23-3)15(24-4)18(27-7)20(30-11)31-14-12(10-22-2)29-19(28-

InChI key

PUSNGFYSTWMJSK-GSZQVNRLSA-N

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Dieser Artikel
423181423173H9262
solubility

water: 100 mg/10 mL, clear, colorless

solubility

-

solubility

-

solubility

-

Quality Level

100

Quality Level

100

Quality Level

200

Quality Level

200

form

powder

form

powder or crystals

form

powder

form

powder

storage temp.

room temp

storage temp.

-

storage temp.

-

storage temp.

-

color

faint beige

color

-

color

-

color

beige

composition

hydroxylpropoxyl content, ~9%

composition

-

composition

-

composition

-

Application

Verdicker für wässrige und nicht-wässrige Systeme, klare Filme mit Fettbeständigkeit, Bindemittel, Schmiermittel, sterischer Stabilisator und Wasser Retentionsmittel.
(Hydroxypropyl)methyl cellulose (HPMC), an inert viscoelastic polymer is used as an emulsifier, thickening and suspending agent similar to animal gelatin. HPMC is used in the development of controlled-delivery medicament.

Features and Benefits

Löst sich in Wasser, reversible Gelbildung beim Erhitzen, nicht-ionisch, bildet keine Komplexe mit ionischen Spezies, oberflächenaktiv und Enzym resistent. Die Lösungen sind pseudoplastisch.

Other Notes

To gain a comprehensive understanding of our extensive range of Polysaccharides for your research, we encourage you to visit our Carbohydrates Category page.

Lagerklasse

11 - Combustible Solids

wgk

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

ppe

Eyeshields, Gloves, type N95 (US)


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Analysenzertifikate (COA)

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Die Dokumentenbibliothek aufrufen

Punit P Shah et al.
Biomaterials, 33(5), 1607-1617 (2011-11-29)
The aim of this study was to develop an effective drug delivery system for the simultaneous topical delivery of two anti-inflammatory drugs, spantide II (SP) and ketoprofen (KP). To achieve this primary goal, we have developed a skin permeating nanogel
Lucas Sievens-Figueroa et al.
International journal of pharmaceutics, 423(2), 496-508 (2011-12-20)
The design and feasibility of a simple process of incorporating stable nanoparticles into edible polymer films is demonstrated with the goal of enhancing the dissolution rate of poorly water soluble drugs. Nanosuspensions produced from wet stirred media milling (WSMM) were
Michelle Lay Teng Ang et al.
Infection and immunity, 82(5), 1850-1859 (2014-02-26)
Tuberculosis remains a major worldwide epidemic because of its sole etiological agent, Mycobacterium tuberculosis. Ethionamide (ETH) is one of the major antitubercular drugs used to treat infections with multidrug-resistant M. tuberculosis strains. ETH is a prodrug that requires activation within
Jeonghoon Han et al.
Aquatic toxicology (Amsterdam, Netherlands), 152, 308-317 (2014-05-13)
In this study, we investigated the effects of the water-accommodated fraction (WAF) of crude oil on the development and reproduction of the intertidal copepod Tigriopus japonicus through life-cycle experiments. Furthermore, we investigated the mechanisms underlying the toxic effects of WAF
Fernando Andrés et al.
Proceedings of the National Academy of Sciences of the United States of America, 111(26), E2760-E2769 (2014-07-01)
In Arabidopsis thaliana environmental and endogenous cues promote flowering by activating expression of a small number of integrator genes. The MADS box transcription factor SHORT VEGETATIVE PHASE (SVP) is a critical inhibitor of flowering that directly represses transcription of these

Questions

1–2 of 2 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

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