02070

Adenosin-5′-triphosphat-P³-[1-(2-nitrophenyl)-ethylester] Dinatriumsalz

≥95% (HPLC)

• Synonym(e): NPE caged ATP, ‘Caged ATP’
• Empirische Formel (Hill-System): C₁₈H₂₁N₆Na₂O₁₅P₃
• CAS-Nummer: 171800-68-3
• Molekulargewicht: 700.29
• UNSPSC Code: 41106305
• PubChem Substance ID: 329747384
• MDL number: MFCD00077294

Eigenschaften

• assay: ≥95% (HPLC)
• storage temp.: −20°C
• SMILES string: [Na+].[Na+].CC(OP([O-])(=O)OP([O-])(=O)OP(O)(=O)OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n2cnc3c(N)ncnc23)c4ccccc4[N+]([O-])=O
• InChI: 1S/C18H23N6O15P3.2Na/c1-9(10-4-2-3-5-11(10)24(27)28)37-41(31,32)39-42(33,34)38-40(29,30)35-6-12-14(25)15(26)18(36-12)23-8-22-13-16(19)20-7-21-17(13)23;;/h2-5,7-9,12,14-15,18,25-26H,6H2,1H3,(H,29,30)(H,31,32)(H,33,34)(H2,19,20,21);;/q;2*+1/p-2/t9?,12-,14-,15-,18-;;/m1../s1
• InChI key: DWGOHIKVVKFGGU-DZHDPEGHSA-L

Beschreibung

Application

Adenosine 5′-triphosphate γ-(1-[2-nitrophenyl]ethyl) ester (“Caged” ATP) is used as a photolyzing substrate of luciferase-mediated firefly bioluminescence and other ATP-dependent photolytic processes. Caged ATP has also been used to study the dynamics of ATP-driven linear molecular motors such as myosin Va. Caged ATP is used to study intracellular mechanisms; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage resulting in a time- and quantity-specific concentration increase of ATP within the cell; Relaxation of muscle fibres by photolysis of caged ATP.

Other Notes

Used to study intracellular mechanisms.; Irradiation with a short light pulse of 360 nm wavelength releases the parent compound from its cage, resulting in a time- and quantity-specific concentration increase of ATP within the cell.; Relaxation of muscle fibres by photolysis of caged ATP[1]; Caged ATP as a tool in active transport research[2]

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H319
• pcodes: P264 - P280 - P305 + P351 + P338 - P337 + P313
• Hazard Classifications: Eye Irrit. 2
• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_c: Not applicable