BP1144

Glimepirid

British Pharmacopoeia (BP) Reference Standard

• Empirische Formel (Hill-System): C₂₄H₃₄N₄O₅S
• CAS-Nummer: 93479-97-1
• Molekulargewicht: 490.62
• UNSPSC Code: 41116107
• NACRES: NA.24
• MDL number: MFCD00878417

Eigenschaften

• grade: pharmaceutical primary standard
• API family: glimepiride
• form: solid
• shelf life: limited shelf life, expiry date on the label
• manufacturer/tradename: BP
• application(s): pharmaceutical; pharmaceutical small molecule
• format: neat
• storage temp.: 2-8°C
• SMILES string: CCC1=C(C)CN(C(=O)NCCc2ccc(cc2)S(=O)(=O)NC(=O)N[C@H]3CC[C@H](C)CC3)C1=O
• InChI: 1S/C24H34N4O5S/c1-4-21-17(3)15-28(22(21)29)24(31)25-14-13-18-7-11-20(12-8-18)34(32,33)27-23(30)26-19-9-5-16(2)6-10-19/h7-8,11-12,16,19H,4-6,9-10,13-15H2,1-3H3,(H,25,31)(H2,26,27,30)/t16-,19-
• InChI key: WIGIZIANZCJQQY-RUCARUNLSA-N
• Gene Information: human ... ABCC8(6833), KCNJ11(3767)

Beschreibung

General description

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Glimepirid wird derzeit zur Behandlung von Typ-2-Diabetes eingesetzt.

Glimepiride BP Reference standard, intended for use in laboratory tests only as specifically prescribed in the British Pharmacopoeia.

Also used in monographs such as:

Glimepiride Tablets

Biochem/physiol Actions

Glimepirid ist ein wirksamer Blocker kardialer K_ATP-Kanäle, aktiviert durch Pinacidil mit einem IC₅₀ von 6,8 nM.

Wirksamer Blocker kardialer K_ATP-Kanäle.

Packaging

Unit quantity: 100 mg. Subject to change. The product is delivered as supplied by the issuing Pharmacopoeia. For the current unit quantity please visit British Pharmacopoeia

Other Notes

Sales restrictions may apply.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Warning
• hcodes: H361
• pcodes: P201 - P202 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 2
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable