B1000000

Betamethason

European Pharmacopoeia (EP) Reference Standard

• Synonym(e): 9α-Fluor-11β,17α,21-trihydroxy-16β-methylpregna-1,4-dien-3,20-dion, 9α-Fluor-16β-methyl-11β,17α,21-trihydroxy-1,4-pregnadien-3,20-dion, 9α-Fluor-16β-methylprednisolon
• Empirische Formel (Hill-System): C₂₂H₂₉FO₅
• CAS-Nummer: 378-44-9
• Molekulargewicht: 392.46
• NACRES: NA.24
• PubChem Substance ID: 329773150
• UNSPSC Code: 41116107
• MDL number: MFCD00062969

Eigenschaften

• biological source: synthetic
• grade: pharmaceutical primary standard
• API family: betamethasone
• packaging: pkg of 60 mg
• manufacturer/tradename: EDQM
• storage condition: protect from light
• color: white
• mp: 235-237 °C (lit.), 235.6 °C (456.1°F at 1013.0 hPa)
• solubility: water: slightly soluble 0.063 g/L at 37 °C
• density: 0.305 g/cm³ at 25 °C (77°F)
• application(s): pharmaceutical (small molecule)
• format: neat
• shipped in: ambient
• SMILES string: [H][C@@]12C[C@H](C)[C@](O)(C(=O)CO)[C@@]1(C)C[C@H](O)[C@@]3(F)[C@@]2([H])CCC4=CC(=O)C=C[C@]34C
• InChI: 1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15-,16-,17-,19-,20-,21-,22-/m0/s1
• InChI key: UREBDLICKHMUKA-DVTGEIKXSA-N
• Gene Information: human ... NR3C1(2908)

Beschreibung

General description

Betamethasone, a synthetic glucocorticoid, belongs to the corticosteroid family of active pharmaceutical ingredients (APIs).

This product is provided as delivered and specified by the issuing Pharmacopoeia. All information provided in support of this product, including SDS and any product information leaflets have been developed and issued under the Authority of the issuing Pharmacopoeia. For further information and support please go to the website of the issuing Pharmacopoeia.

Application

Betamethasone EP reference standard may be used as a pharmaceutical primary standard for the determination of the analyte in pharmaceutical formulations by chromatographic and spectrophotometric techniques.

Packaging

Dieses Produkt wird, wie von der entsprechenden Pharmakopöe geliefert, angeboten. Die aktuellen Mengeneinheiten finden Sie im Referenzsubstanzen-Katalog der EDQM.

Other Notes

Kann Verkaufsbeschränkungen unterliegen.

Sicherheitshinweise

• pictograms: GHS08
• signalword: Danger
• hcodes: H360FD,H373
• pcodes: P202 - P260 - P280 - P308 + P313 - P405 - P501
• Hazard Classifications: Repr. 1B - STOT RE 2
• target_organs: Liver,Kidney,Endocrine system
• Lagerklasse: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable