78251

(Z)-Guggulsteron

analytical standard

• Synonym(e): (17Z)-Pregna-4,17(20)-dien-3,16-dion, 4,17(20)-trans-Pregnadien-3,16-dion
• Empirische Formel (Hill-System): C₂₁H₂₈O₂
• CAS-Nummer: 39025-23-5
• Molekulargewicht: 312.45
• UNSPSC Code: 85151701
• PubChem Substance ID: 329768130
• MDL number: MFCD01310757

Eigenschaften

• grade: analytical standard
• Quality Segment: 100
• assay: ≥95.0% (HPLC)
• shelf life: limited shelf life, expiry date on the label
• technique(s): HPLC: suitable, gas chromatography (GC): suitable
• application(s): food and beverages
• format: neat
• SMILES string: [H][C@@]12CCC3=CC(=O)CC[C@]3(C)[C@@]1([H])CC[C@]4(C)\C(=C\C)C(=O)C[C@@]24[H]
• InChI: 1S/C21H28O2/c1-4-16-19(23)12-18-15-6-5-13-11-14(22)7-9-20(13,2)17(15)8-10-21(16,18)3/h4,11,15,17-18H,5-10,12H2,1-3H3/b16-4+/t15-,17+,18+,20+,21-/m1/s1
• InChI key: WDXRGPWQVHZTQJ-OSJVMJFVSA-N

Beschreibung

Application

Refer to the product′s Certificate of Analysis for more information on a suitable instrument technique. Contact Technical Service for further support.

Biochem/physiol Actions

(Z)-Guggulsterone is a natural product that lowers cholesterol due to its function as an antagonist ligand for the bile acid receptor. (Z)-Guggulsterone is a nuclear hormone receptor that regulates the transcription of several genes involved in cholesterol metabolism and plays a role in cholesterol level regulation. (Z)-Guggulsterone is also a selective farnesoid X receptor (FXR) modulator.

(Z)-Guggulsterone is an antagonist ligand for bile acid receptor.

Sicherheitshinweise

• pictograms: GHS07
• signalword: Warning
• hcodes: H335
• pcodes: P261 - P271 - P304 + P340 + P312 - P403 + P233 - P405 - P501
• Hazard Classifications: STOT SE 3
• target_organs: Respiratory system
• Lagerklasse: 11 - Combustible Solids
• wgk: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable