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Merck

44577

Sigma-Aldrich

Doxycyclin -hyclat

≥98.0% (TLC)

Synonym(e):

Doxycyclin-hydrochlorid Hemiethanolat Hemihydrat

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About This Item

Empirische Formel (Hill-System):
C22H24N2O8 · HCl · 0.5H2O · 0.5C2H6O
CAS-Nummer:
Molekulargewicht:
512.94
Beilstein:
5702728
MDL-Nummer:
UNSPSC-Code:
51101500
PubChem Substanz-ID:

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Biologische Quelle

synthetic

Assay

≥98.0% (TLC)

Form

powder

Verunreinigungen

≤5% water
≤7% ethanol

Farbe

faintly yellow to yellow

Löslichkeit

H2O: 50 mg/mL, clear, yellow-green

Wirkungsspektrum von Antibiotika

Gram-negative bacteria
Gram-positive bacteria
mycoplasma
parasites

Wirkungsweise

protein synthesis | interferes

SMILES String

Cl[H].Cl[H].[H]O[H].CCO.C[C@@H]1C2[C@H](O)C3[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]3(O)C(O)=C2C(=O)c4c(O)cccc14.C[C@@H]5C6[C@H](O)C7[C@H](N(C)C)C(O)=C(C(N)=O)C(=O)[C@@]7(O)C(O)=C6C(=O)c8c(O)cccc58

InChI

1S/2C22H24N2O8.C2H6O.2ClH.H2O/c2*1-7-8-5-4-6-9(25)11(8)16(26)12-10(7)17(27)14-15(24(2)3)18(28)13(21(23)31)20(30)22(14,32)19(12)29;1-2-3;;;/h2*4-7,10,14-15,17,25,27-29,32H,1-3H3,(H2,23,31);3H,2H2,1H3;2*1H;1H2/t2*7-,10?,14?,15-,17-,22-;;;;/m00..../s1

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Allgemeine Beschreibung

Chemical structure: tetracycline

Biochem./physiol. Wirkung

Wirkungsweise: Doxycyclinhyclat hemmt die Entzündungsreaktion auf die Spirochäte Borrelia burgdorferi, den Erreger der Lyme-Krankheit.

Wirkungsspektrum: Wirksam gegen einen Breitspektrum-Inhibitor von Matrix-Metallproteinasen in vivo.

Sonstige Hinweise

Keep container tightly closed in a dry and well-ventilated place. Keep in a dry place.
This product has been replaced by D9891-SIGMA | Doxycycline hyclate ≥98% (TLC)

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Analysenzertifikate (COA)

Lot/Batch Number

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  1. Which document(s) contains shelf-life or expiration date information for a given product?

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  5. Is doxycycline hyclate soluble in DMSO?

    According to literature sources, doxycycline hyclate is soluble in DMSO at a concentration of 100 mM.

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