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328634

NMP

anhydrous, 99.5%

1 of 1 reviewers received a sample product or took part in a promotion

Synonym(e):

1-Methyl-2-Pyrrolidinon, N-Methyl-2-pyrrolidon, M-PYROL, NMP

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Über diesen Artikel

Empirische Formel (Hill-System):
C5H9NO
CAS-Nummer:
Molekulargewicht:
99.13
NACRES:
NA.21
PubChem Substance ID:
UNSPSC Code:
12352005
EC Number:
212-828-1
MDL number:
Beilstein/REAXYS Number:
106420
Assay:
99.5%
Grade:
anhydrous
Bp:
202 °C (lit.), 81-82 °C/10 mmHg (lit.)
Vapor pressure:
0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)
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Produktname

1-Methyl-2-pyrrolidon, anhydrous, 99.5%

grade

anhydrous

Quality Segment

vapor density

3.4 (vs air)

vapor pressure

0.29 mmHg ( 20 °C), 0.99 mmHg ( 40 °C)

assay

99.5%

form

liquid

autoignition temp.

518 °F

expl. lim.

9.5 %

impurities

<0.005% water

refractive index

n20/D 1.47 (lit.)

pH

7.7-10.0 (20 °C, 100 g/L)

bp

202 °C (lit.), 81-82 °C/10 mmHg (lit.)

mp

−24 °C (lit.)

density

1.028 g/mL at 25 °C (lit.)

SMILES string

CN1CCCC1=O

InChI

1S/C5H9NO/c1-6-4-2-3-5(6)7/h2-4H2,1H3

InChI key

SECXISVLQFMRJM-UHFFFAOYSA-N

General description

Our anhydrous solvents deliver exceptionally low water content, making them the ideal choice for moisture-sensitive laboratory applications. Packaged in the exclusive Sure/Seal septum bottle system, they are reliably protected against moisture ingress from first use to last drop. The innovative Sure/Seal closure combines an advanced plug-style liner with an airtight elastomer and crimp cap design to ensure consistent product integrity. Three unique liner materials provide optimal chemical compatibility across a broad range of solvents. Sure/Seal packaging is proven to maintain anhydrous conditions even after repeated punctures. With more than 70 products across all major solvent families, available in pack sizes from 100 mL to 2 L, the portfolio meets virtually every laboratory need. By choosing ready-to-use anhydrous solvents in Sure/Seal packaging, researchers eliminate the need for time-consuming and hazardous in-house solvent drying and distillation - saving time, reducing risk, and improving reproducibility.

Application

Anhydrous solvents in Sure/Seal packaging are essential wherever water contamination would compromise experimental results. They are widely used in moisture-sensitive applications such as organic synthesis - including Grignard reactions, organometallic chemistry, and catalysis - as well as in peptide, oligonucleotide, and pharmaceutical synthesis.

Packaging

Other Notes

Pure-Pac® II Behälter benötigen Micromatic MacroVentilverbinder (Z560723) zur Lösungsmittel-Dispensierung.

Legal Information

Sure/Seal is a trademark of Sigma-Aldrich Co. LLC
Pure-Pac is a registered trademark of Merck KGaA, Darmstadt, Germany

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Dieser Artikel
MX1394
description

anhydrous, 99.5%

description

for Peptide Synthesis

Quality Level

200

Quality Level

200

grade

anhydrous

grade

-

assay

99.5%

assay

≥99.5% (GC)

form

liquid

form

liquid

density

1.028 g/mL at 25 °C (lit.)

density

1.03 g/cm3 at 20 °C

expl. lim.

9.5 %

expl. lim.

-


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pictograms

Health hazardExclamation mark

signalword

Danger

Hazard Classifications

Eye Irrit. 2 - Repr. 1B - Skin Irrit. 2 - STOT SE 3

target_organs

Respiratory system

Lagerklasse

6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects

flash_point_f

195.8 °F - Pensky-Martens closed cup

flash_point_c

91 °C - Pensky-Martens closed cup

ppe

Eyeshields, Gloves, type ABEK (EN14387) respirator filter


Zulassungslistungen

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872-50-4

CAS No.

872-50-4

CAS No.


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Analysenzertifikate (COA)

Lot/Batch Number

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Questions

1–7 of 7 Questions  
  1. How can I determine the shelf life / expiration / retest date of this product?

    1 answer
    1. If this product has an expiration or retest date, it will be shown on the Certificate of Analysis (COA, CofA). If there is no retest or expiration date listed on the product's COA, we do not have suitable stability data to determine a shelf life. For these products, the only date on the COA will be the release date; a retest, expiration, or use-by-date will not be displayed.
      For all products, we recommend handling per defined conditions as printed in our product literature and website product descriptions. We recommend that products should be routinely inspected by customers to ensure they perform as expected.
      For products without retest or expiration dates, our standard warranty of 1 year from the date of shipment is applicable.
      For more information, please refer to the Product Dating Information document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/418/501/product-dating-information-06-25-mk.pdf

      Helpful?

  2. Is NMP compatible with PTFE?

    1 answer
    1. N-Methylpyrrolidone (NMP) is a commonly used solvent, and it is compatible with polytetrafluoroethylene (PTFE).

      Helpful?

  3. Is NMP supplied under N2 or air?

    1 answer
    1. This product is packaged under nitrogen.

      Helpful?

  4. How is shipping temperature determined? And how is it related to the product storage temperature?

    1 answer
    1. Products may be shipped at a different temperature than the recommended long-term storage temperature. If the product quality is sensitive to short-term exposure to conditions other than the recommended long-term storage, it will be shipped on wet or dry-ice. If the product quality is NOT affected by short-term exposure to conditions other than the recommended long-term storage, it will be shipped at ambient temperature. As shipping routes are configured for minimum transit times, shipping at ambient temperature helps control shipping costs for our customers. For more information, please refer to the Storage and Transport Conditions document: https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/marketing/global/documents/316/622/storage-transport-conditions-mk.pdf

      Helpful?

  5. Is this NMP suitable for HPLC and GC analysis?

    1 answer
    1. Yes, this product is suitable for HPLC and GC analysis. This anhydrous NMP can be effectively used in environments where moisture must be minimized, which is often critical in analytical techniques like HPLC and GC.

      Helpful?

  6. Does it have molecular shieve in the bottle?

    1 answer
    1. Molecular sieves are not included with this anhydrous material. However, the 18L size is packaged in the Pure-Pac II container, and the 100 mL to 2L volumes utilize Sure/Seal closures. Please see the links below to learn more about each package type:

      Sure/Seal
      https://www.sigmaaldrich.com/technical-documents/technical-article/chemistry-and-synthesis/organic-reaction-toolbox/sureseal

      Pure-Pac
      https://www.sigmaaldrich.com/deepweb/assets/sigmaaldrich/product/documents/391/402/al_techbull_al201.pdf

      Helpful?

  7. Could you please provide me with the dimensions of the bottle containing the product 328634-2L (1-Methyl-2-pyrrolidinone)?

    1 answer
    1. The packaging description for the bottle is as follows:
      • Bottle Type: Narrow Neck Glass Bottle
      • Capacity: 2500 ml (Nominal), 2750 ml (Brimful)
      • Closure Type: Crown Cap (Sure/Seal)
      • Glass Type: Amber Glass (Hydrolytic Class III)
      • Diameter: 139 mm
      • Height: 286 mm
      • Height with Cap: 293 mm
      • Thread Diameter: 32 mm
      • Thread Type: 32 mm
      • Inner Diameter of Opening: 17 mm

      Helpful?

Reviews

Active Filters

  1. boston, ma
    • Reviews 2
    • Votes 4
    4 out of 5 stars.

    nice but also

    good product, but inconsistent stock. Many times unavailable.

    Helpful?