MAB5424

Anti-Prion Protein Antibody

Chemicon^®, from mouse

• Synonym(e): PrP, CD230
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: monoclonal
• Application: ELISA, IHC, WB
• Citations: 2

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: monoclonal
• species reactivity: sheep, mouse, mule deer, bovine, elk
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, immunohistochemistry: suitable, western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_000311.3, NM_001080121.1, NM_001080122.1, NM_001080123.1, NM_183079.2
• UniProt accession no.: P04156
• shipped in: dry ice
• target post-translational modification: unmodified
• Gene Information: human ... PRNP(5621)

Beschreibung

Immunogen

Recombinant PrP amino acids 23-237.

Application

Anti-Prion Protein Antibody is an antibody against Prion Protein for use in ELISA, WB, IH.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Western blot: 1:50,000-1:200,000

Immunohistochemistry: 1:100-1:500. Epitope must be re-exposed in fixed tissue by pretreatment of tissue using one of the following procedures:

a. formic acid for 10 minutes at room temperature

b. hydrolytic autoclaving

c. heat induced epitope retrieval

ELISA: 1:20,000-1:50,000

Optimal working dilutions must be determined by end user.

Biochem/physiol Actions

Reacts with prion protein (PrP) from bovine, sheep, mule deer, elk and mouse. The monoclonal recognizes both protease sensitive and protease resistant forms of PrP (after denaturing).

Physical form

Format: Purified

Purified immunoglobulin. Liquid in PBS. Contains no preservative.

Preparation Note

Maintain at -20°C to -70°C in undiluted aliquots for up to 6 months after date of receipt.

Avoid repeated freeze/thaw cycles.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable