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MAB427

Sigma-Aldrich

Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a

ascites fluid, clone mAB 1a, Chemicon®

Synonym(e):

Anti-CACNL1A3, Anti-CCHL1A3, Anti-Cav1.1, Anti-HOKPP, Anti-HOKPP1, Anti-MHS5, Anti-TTPP1, Anti-hypoPP

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About This Item

UNSPSC-Code:
12352203
eCl@ss:
32160702
NACRES:
NA.41

Biologische Quelle

mouse

Qualitätsniveau

100

Antikörperform

ascites fluid

Antikörper-Produkttyp

primary antibodies

Klon

mAB 1a, monoclonal

Speziesreaktivität

rabbit, mouse, human, rat

Hersteller/Markenname

Chemicon®

Methode(n)

flow cytometry: suitable
immunoprecipitation (IP): suitable
western blot: suitable

Isotyp

IgG1

NCBI-Hinterlegungsnummer

NM_000069.2

UniProt-Hinterlegungsnummer

Q13698

Versandbedingung

dry ice

Posttranslationale Modifikation Target

unmodified

Spezifität

Dihydropyridine calcium channel, a1 subunit as determined by Western blot (~210 kDa), immunoprecipitation and functional test. Membrane preparations are recommended. The mouse muscle cell line, BC3H1 functions as a good positive control cell line. Reactive with L-type calcium channel alpha1 subunit. Specific for small cell carcinoma and neuroblastoma by FACS analysis. No interaction with squamous cell carcinoma or with cardiac calcium chanel isoforms.

Anwendung

Anti-Dihydropyridine-sensitive Calcium Channel α 1 Subunit Antibody, clone 1a is an antibody against Dihydropyridine-sensitive Calcium Channel α 1 Subunit for use in FC, IP & WB.
Western blot, immunoprecipitation and FACS.

Optimal working dilutions must be determined by end user.

Verlinkung

Replaces: 06-422

Rechtliche Hinweise

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

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Lagerklassenschlüssel

10 - Combustible liquids

WGK

WGK 1

Flammpunkt (°F)

Not applicable

Flammpunkt (°C)

Not applicable

Analysenzertifikate (COA)

Suchen Sie nach Analysenzertifikate (COA), indem Sie die Lot-/Chargennummer des Produkts eingeben. Lot- und Chargennummern sind auf dem Produktetikett hinter den Wörtern ‘Lot’ oder ‘Batch’ (Lot oder Charge) zu finden.

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Die Dokumentenbibliothek aufrufen

T Szikra et al.
Neuroscience, 141(1), 143-155 (2006-05-10)
Vertebrate photoreceptors consist of strictly delimited subcellular domains: the outer segment, ellipsoid, cell body and synaptic terminal, each hosting crucial cellular functions, including phototransduction, oxidative metabolism, gene expression and transmitter release. We used optical imaging to explore the spatiotemporal dynamics
Ryutaro Akiba et al.
Frontiers in cellular neuroscience, 13, 16-16 (2019-02-26)
Quantitative and qualitative evaluation of synapses is crucial to understand neural connectivity. This is particularly relevant now, in view of the recent advances in regenerative biology and medicine. There is an urgent need to evaluate synapses to access the extent
Nazarul Hasan et al.
Visual neuroscience, 33, E009-E009 (2016-07-30)
Cacna1s encodes the α1S subunit (Cav1.1) of voltage-dependent calcium channels, and is required for normal skeletal and cardiac muscle function, where it couples with the ryanodine receptor to regulate muscle contraction. Recently CACNA1S was reported to be expressed on the
R G Parton et al.
The Journal of cell biology, 136(1), 137-154 (1997-01-13)
Caveolae, flask-shaped invaginations of the plasma membrane, are particularly abundant in muscle cells. We have recently cloned a muscle-specific caveolin, termed caveolin-3, which is expressed in differentiated muscle cells. Specific antibodies to caveolin-3 were generated and used to characterize the
Localization of Cacna1s to ON bipolar dendritic tips requires mGluR6-related cascade elements.
Tummala, SR; Neinstein, A; Fina, ME; Dhingra, A; Vardi, N
Investigative Ophthalmology & Visual Science null
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