MAB4133

Anti-p16 Antibody, clone D25

clone D25, Chemicon^®, from mouse

• Synonym(e): INK4a, MTS1, CDK4IN, CDKN2
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: D25, monoclonal
• Application: IHC, WB
• Citations: 13

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: D25, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): immunohistochemistry: suitable, western blot: suitable
• isotype: IgG1
• NCBI accession no.: NM_000077.3, NM_058195.2, NM_058197.3
• UniProt accession no.: Q8N726
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... CDKN2A(1029)

Beschreibung

Immunogen

Recombinant p16 fusion protein from E. coli.

Application

Anti-p16 Antibody, clone D25 is a Mouse Monoclonal Antibody for detection of p16 also known as INK4a, MTS1, CDK4IN, CDKN2 & has been validated in WB & IHC.

Immunoblotting

Immunohistochemistry

Optimal working dilutions must be determined by end user.

Research Category
Epigenetics & Nuclear Function

Research Sub Category
Cell Cycle, DNA Replication & Repair

Biochem/physiol Actions

P16* is a major tumor suppressor gene, which is known to be deleted or mutated in many types of human cancers. Antibody MAB4133 binds specifically to p16 in its recombinant or native form. It also recognizes p16 expressed by melanomas and neve in situ.

Physical form

Format: Purified

Liquid in phosphate buffer, containing azide as a preservative.

Preparation Note

Maintain refrigerated at 2-8°C in undiluted aliquots for up to 12 months.

Analysis Note

Control
POSITIVE CONTROL: HeLa cells

colon carcinoma

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Replaces: 04-239

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• Lagerklasse: 12 - Non Combustible Liquids