MAB1476

Anti-Chymotrypsin Antibody, Human Pancreas

ascites fluid, Chemicon^®

• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Clone: monoclonal
• Species reactivity: human
• Application: ELISA, IHC
• Citations: 3

Eigenschaften

• biological source: mouse
• antibody form: ascites fluid
• antibody product type: primary antibodies
• clone: monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): ELISA: suitable, immunohistochemistry: suitable
• isotype: IgG3
• NCBI accession no.: NM_001907.1
• UniProt accession no.: P40313
• shipped in: dry ice
• target post-translational modification: unmodified

Beschreibung

General description

Chymotrypsin is an intestinal proteolytic enzyme composed of three polypeptide chains. It is produced in the pancrease as the inactive form chymotrypsinogen (single 245 aa chain). Chymotrypsinogen is activated in the duodenum by trypin and other active chymotrypsin molecules. It preferentially catalyzes the hydrolysis of peptide bonds involving L-isomers of tyrosine, phenylalanine and tryptophan. It also readily acts upon amides and esters of susceptible amino acids. Chymotrypsin catalyzes the hydrolysis of bonds of leucyl, methionyl, asparaginyl and glutamyl residues.

Immunogen

Purified human pancreatic chymotrypsin.

Application

Detect Chymotrypsin using this Anti-Chymotrypsin Antibody, Human Pancreas validated for use in ELISA, IH.

ELISA

Immunohistochemistry: 1:1000.

Optimal working dilution must be determined by the end user.

Research Category
Metabolism

Research Sub Category
Enzymes & Biochemistry

Biochem/physiol Actions

Recognizes chymotrypsin.

Physical form

Liquid. Contains no preservative.

Preparation Note

Maintain at -20°C in convenient aliquots for up to 12 months after date of receipt. Avoid repeated freeze/thaw cycles.

During shipment, small volumes of product will occasionally become entrapped in the seal of the product vial. For products with volumes of 200μL or less, we recommend gently tapping the vial on a hard surface or briefly centrifuging the vial in a tabletop centrifuge to dislodge any liquid in the container′s cap.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable