FCMAB207F

Milli-Mark^® Anti-CD71-FITC Antibody, clone Ber-T9

clone Ber-T9, Milli-Mark^®, from mouse

• Synonym(e): Transferrin receptor protein 1, TfR1, TfR, T9, p90
• UNSPSC Code: 12352203
• NACRES: NA.44
• eCl@ss: 32160702
• Conjugate: FITC conjugate
• Clone: Ber-T9, monoclonal
• Application: FACS
• Citations: 1

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: FITC conjugate
• antibody form: purified immunoglobulin
• antibody product type: primary antibodies
• clone: Ber-T9, monoclonal
• species reactivity: human
• manufacturer/tradename: Milli-Mark^®
• technique(s): flow cytometry: suitable
• isotype: IgG1κ
• NCBI accession no.: NP_003225
• UniProt accession no.: P02786
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... TFRC(7037)

Beschreibung

General description

190 kDa (Goding, 2002)

CD71 is a 190 kDa disulfide-bonded homodimeric type II transmembrane glycoprotein. CD71 is the receptor for transferrin. CD71 is involved in iron (Fe3+) uptake, and expression is regulated by the metabolic demand for iron, which is essential for the growing cell (Goding, 2002). CD71 is more abundantly expressed in rapidly dividing cells than quiescent cells (Newman, 1982; Sutherland, 1981). In normal tissues, high expression of CD71 is seen in the placental trophoblast and hemoglobin-synthesizing reticulocytes (Newman, 1982) but expression is lost in mature erythrocytes (Sutherland, 1981). Anti-CD71, Ber-79, was included in the Fifth International Workshop and Conference on Human Leucocyte Differentiation Antigens, and studies by a number of laboratories confirmed its reactivity with CD71 (Boeker, 1995).

Application

Detect CD71 using this Milli-Mark Anti-CD71-FITC Antibody, clone Ber-T9 validated for use in FC.

Research Category
Inflammation & Immunology

Research Sub Category
Immunoglobulins & Immunology

Biochem/physiol Actions

Antibody recognizes Human CD71 antigen.

Physical form

Protein A purified

Purified Mouse monoclonal IgG1 conjugated to FITC in 0.05M Tris-HCl buffer with 1% BSA, Sodium Azide at 0.097% at pH 7.2.

Preparation Note

Maintain refrigerated at 2-8°C protected from light in undiluted aliquots for up to 6 months from date of receipt.

Analysis Note

Control
Human Lymphocytes

Evaluated by flow cytometry using human lymphocytes

Legal Information

MILLI-MARK is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2