CBL468

Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6

clone HC1/6, Chemicon^®, from mouse

• Synonym(e): CD31
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: HC1/6, monoclonal
• Application: FACS, IHC (p), IP
• Citations: 15

Eigenschaften

• biological source: mouse
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: purified immunoglobulin
• clone: HC1/6, monoclonal
• species reactivity: human
• manufacturer/tradename: Chemicon^®
• technique(s): flow cytometry: suitable, immunohistochemistry (formalin-fixed, paraffin-embedded sections): suitable, immunoprecipitation (IP): suitable
• isotype: IgG1
• NCBI accession no.: NM_000442.3
• UniProt accession no.: P16284
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... PECAM1(5175)

Beschreibung

Immunogen

Epitope: domains 3-6 of human PECAM-1

Application

Anti-PECAM-1 Antibody, domains 3-6 of human PECAM-1, clone HC1/6 is an antibody against PECAM-1 for use in FC, IH, IH(P) & IP.

Studies of the role of CD31 in leucocyte migration into inflammatory sites and in the process of angiogenesis

This antibody will stain frozen tissue sections

Suitable for immunoprecipitation studies

Suitable for flow cytometry either indirectly or directly when labelled with FITC or R-PE

Suitable for use on formalin fixed paraffin embedded sections after protease pre-treatment.

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Reacts with a 130-140 kDa transmembranous glycoprotein that is expressed widely amongst cells of the vascular compartment. CD31 is expressed on platelets, cultured endothelial cells, monocytes, normal tissue macrophages in tonsil, lung and kidney as well as in skin biopsies from conditions such as sarcoidosis and lepromatous leprosy.
FUSION PARTNER: P3-x63Ag8.653 myeloma cell line

Physical form

Format: Purified

Analysis Note

Control
Activated microglial cells

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 2
• flash_point_f: Not applicable
• flash_point_c: Not applicable