ABS538

Anti-FABP1 Antibody

serum, from rabbit

• Synonym(e): Fatty acid-binding protein, liver, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, p14
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: -

Eigenschaften

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: serum
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human, mouse
• species reactivity (predicted by homology): rat (based on 100% sequence homology)
• technique(s): western blot: suitable
• NCBI accession no.: NP_036688
• UniProt accession no.: P02692
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: rat ... Fabp1(24360)

Beschreibung

General description

FABP1, also known as Fatty acid-binding protein, Liver Fatty acid-binding protein, Fatty acid-binding protein 1, Liver-type fatty acid-binding protein, L-FABP, Squalene- and sterol-carrier protein, SCP, Z-protein, or p14, and encoded by the gene FABP1/FABPL, is an important fatty acid binding and transport protein. FABP1 is produced in the liver and is part of a family of lipid carrier proteins. FABP1 facilitate the transfer of fatty acids between extra and intracellular membranes. FABP1 level in the blood is used as a biomarker for obesity and type II diabetes. Additionally, recent research indicates that FABP1 can modulate stellate cell activation and this may lead to diet-induced nonalcoholic fatty liver disease, thus FABP1 is a key focus of metabolic research.

~ 14 kDa observed

Immunogen

Recombinant protein corresponding to rat FABP1.

Application

Anti-FABP1 Antibody detects level of FABP1 & has been published & validated for use in FABP1.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected FABP1 in wild type mouse liver cytosol and not in LFABP-1 -/- mouse liver cytosol.

Analysis Note

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: A 1:1,000 dilution of this antibody detected FABP1 in 10 µg of human liver tissue lysate.

Sicherheitshinweise

• Lagerklasse: 10 - Combustible liquids
• wgk: WGK 1