ABS521

Anti-RSK4 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Q9UK32, KS6A6_HUMAN, RPS6KA6, RSK4, Q9UK32, B2R854, Q6FHX2, Q8WX28, Q9H4S6, Ribosomal protein S6 kinase alpha-6, p90RSK6
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: rat
• Speziesreaktivität (Voraussage durch Homologie): human (based on 100% sequence homology), bovine (based on 100% sequence homology)
• Methode(n): immunoprecipitation (IP): suitable; western blot: suitable
• NCBI-Hinterlegungsnummer: NP_055311
• UniProt-Hinterlegungsnummer: Q9UK32
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... RPS6KA6(27330)

Beschreibung

Allgemeine Beschreibung

RSK1, RSK2, RSK3, and RSK4 (ribosomal protein S6 kinase, 90 kDa, polypeptide 1,2,3, and 4; S6K-alpha 1,2,3, and 4) are Ser/Thr kinases which are activated by MAP Kinases. Ribosomal S6-kinase 4 (RSK4) is thought to be mapped in the critical region that is commonly deleted in X-linked deafness type 3, mental retardation, and choroideremia. It may be involved in normal neuronal development. RSK4 is also thought to play a role in non-growth factor signaling and may also be important in tumor suppression.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of Human RSK4.

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Kinasen & Phosphatasen

Allgemeine Posttranslationsmodifikation

Immunoprecipitation analysis: 10 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.5 mg PC12 or EGF treated PC12 cell lysate
Immunoprecipitation analysis: 5 ug of Cat. No. ABS521, Anti-RSK4 was used to immunoprecipitate RSK4 in 0.665mg of PC12 cell lysate. Uncharacterized bands may be detected at high antibody concentration or longer exposures

This Anti-RSK4 Antibody is validated for use in Western Blotting and Immunoprecipitation for the detection of RSK4.

Qualität

Evaluated by Western Blotting in rat PC12 cell lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected RSK4 in 10 µg of rat PC12 cell lysate.

Zielbeschreibung

~83 kDa observed. Uncharacterized band(s) may appear in some lysates.

Verlinkung

Replaces: 04-1132

Physikalische Form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Sonstige Hinweise

Concentration: Please refer to lot specific datasheet.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 12 - Non Combustible Liquids
• WGK: WGK 1
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable