ABS448

Anti-CSN8 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): CSN8 Antibody, COP9 signalosome complex subunit 8, SGN8, JAB1-containing signalosome subunit 8, CSN8
• UNSPSC-Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Eigenschaften

• Biologische Quelle: rabbit
• Qualitätsniveau: 100
• Antikörperform: affinity isolated antibody
• Antikörper-Produkttyp: primary antibodies
• Klon: polyclonal
• Aufgereinigt durch: affinity chromatography
• Speziesreaktivität: human
• Methode(n): western blot: suitable
• UniProt-Hinterlegungsnummer: Q99627
• Versandbedingung: wet ice
• Posttranslationale Modifikation Target: unmodified
• Angaben zum Gen: human ... COPS8(10920)

Beschreibung

Allgemeine Beschreibung

COP9 signalosome complex subunit 8 (CSN8, COPS8), also known as Signalosome subunit 8 (SGN8), is a nuclear-enriched protein complex belonging to the CSN8 family. It is comprised of eight subunits that interact with deubiquitinating enzymes and protein kinases. The CSN complex is involved in the regulation of various signaling and developmental processes, including DNA repair, cell cycle regulation, embryogenesis, axonal guidance, MAPK cascade, immune response, and hormonal signaling.

Spezifität

This antibody recognizes the C-terminus of CSN8.

Immunogen

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of human CSN8.

Anwendung

Research Category
Zelluläre Signaltransduktion

Research Sub Category
Entwicklungsabhängige Signalübertragung

Anti-CSN8 Antibody is a highly specific rabbit polyclonal antibody, that targets COP9 signalosome complex subunit 8 & has been tested in western blotting.

Qualität

Evaluated by Western Blotting in human liver tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected CSN8 in 15 µg of human liver tissue lysate.

Zielbeschreibung

~27 and ~30 kDa observed. Uniprot describes 2 isoforms at ~18 kDa and ~23 kDa Uncharacterized bands may appear in some lysate(s).

Verlinkung

Replaces: MABN1028

Physikalische Form

Antigen Affinity Purified

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Lagerung und Haltbarkeit

Stable for 1 year at 2-8°C from date of receipt.

Hinweis zur Analyse

Control
Human liver tissue lysate

Sonstige Hinweise

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Haftungsausschluss

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklassenschlüssel: 10 - Combustible liquids
• WGK: WGK 2
• Flammpunkt (°F): Not applicable
• Flammpunkt (°C): Not applicable