ABN481

Anti-Synaptopodin Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): Synaptopodin, SYNPO
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: IHC, WB
• Citations: 3

Eigenschaften

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: rat, human
• technique(s): immunohistochemistry: suitable, western blot: suitable
• UniProt accession no.: Q8N3V7
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... SYNPO(11346)

Beschreibung

General description

Synaptopodin (SYNPO) is an actin-associated protein that may play an important role in modulating actin-based shape and motility of dendritic spines and renal podocyte foot processes. It is expressed in the cerebral cortex. Mutations in SYNPO may be associated with nephrotic syndrome.

~95 kDa observed. Uniprot describes three isoforms at ~74 kDa, ~96 kDa, and ~97 kDa Uncharacterized bands may appear in some lysates.

Immunogen

Epitope: Near C-terminus.

KLH-conjugated linear peptide corresponding to a sequence near the C-terminus of human SYNPO.

Application

Detect Synaptopodin using this rabbit polyclonal antibody, Anti-Synaptopodin Antibody validated for use in western blotting & IHC.

Immunohistochemistry Analysis: 2.5 µg/mL from a representative lot detected SYNPO in human brain tissue.

Research Category
Neuroscience

Research Sub Category
Developmental Neuroscience

Physical form

Affinity purified.

Purified rabbit polyclonal in buffer containing PBS with up to 0.1% sodium azide.

Preparation Note

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Rat brain tissue lysate

Evaluated by Western Blotting in rat brain tissue lysate.

Western Blotting Analysis: 2 µg/mL of this antibody detected SYNPO in 15 µg of rat brain tissue lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• wgk: WGK 2
• Lagerklasse: 12 - Non Combustible Liquids