ABE473

Anti-hRNF20 Antibody

from rabbit, purified by affinity chromatography

• Synonym(e): E3 ubiquitin-protein ligase BRE1A, BRE1-A, hBRE1, RING finger protein 20, hRNF20
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: -

Eigenschaften

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: human, rat, mouse
• technique(s): western blot: suitable
• NCBI accession no.: NP_062538
• UniProt accession no.: Q5VTR2
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... RNF20(56254)

Beschreibung

General description

BRE1-A (E3 ubiquitin-protein ligase BRE1A) also known by it′s gene name hRNF20, plays a role in histone code and gene regulation as a component of the RNF20/40 E3 ubiquitin-protein ligase complex. That complex mediates monoubiquitination of ′Lys-120′ of histone H2B,which is a specific tag for epigenetic transcriptional activation as well as a prerequisite for histone H3 ′Lys-4′ (H3K4me) and ′Lys-79′ (H3K79me) methylation.

~113 kDa observed

Immunogen

GST-tagged recombinant protein corresponding to human hRNF20.

Application

This hRNF20 antibody is validated for use in WB for the detection of the hRNF20 protein.

Analysis Note

Evaluated by Western Blotting in A431 cell lysate.

Western Blotting Analysis: A 1:1,000 dilution from a representative lot detected hRNF20 in 10 µg of A431 cell lysate.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• wgk: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable