AB3639

Anti-Endonuclease G Antibody

Chemicon^®, from rabbit

• Synonym(e): EndoG
• UNSPSC Code: 12352203
• NACRES: NA.41
• eCl@ss: 32160702
• Conjugate: unconjugated
• Clone: polyclonal
• Application: WB
• Citations: 11

Eigenschaften

• biological source: rabbit
• Quality Segment: 100
• conjugate: unconjugated
• antibody form: affinity purified immunoglobulin
• antibody product type: primary antibodies
• clone: polyclonal
• purified by: affinity chromatography
• species reactivity: mouse, rat, human
• manufacturer/tradename: Chemicon^®
• technique(s): western blot: suitable
• NCBI accession no.: NM_004435.2
• UniProt accession no.: Q14249
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... ENDOG(2021) ; mouse ... Endog(13804) ; rat ... Endog(362100)

Beschreibung

Immunogen

Synthetic peptide corresponding to amino acids 55 to 70 of human EndoG (GGPRGPGELAKYGLP).

Application

Anti-Endonuclease G Antibody is an antibody against Endonuclease G for use in WB.

Research Category
Apoptosis & Cancer

Research Sub Category
Apoptosis - Additional

Western blotting (1-2μg/mL)

Optimal working dilutions must be determined by the end user.

Biochem/physiol Actions

Recognizes Endonuclease G (EndoG), a mitochondrion-specific nuclease that translocates to the nucleus and cleaves chromatin DNA during apoptosis. EndoG is specifically activated by apoptotic stimuli and is able to induce nucleosomal fragmentation of DNA independently of caspase and DFF/CAD (1,2).

Physical form

Affinity purified immunoglobulin. Liquid in PBS containing 0.02% sodium azide.

Preparation Note

Maintain at 2-8ºC for 12 months.

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Legal Information

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Sicherheitshinweise

• Lagerklasse: 12 - Non Combustible Liquids
• Was ist los?: WGK 2